UniProt P0AFF6
Transcription termination/antitermination protein NusA (P0AFF6)
Transcription termination/antitermination protein NusA (UniProt P0AFF6): 13 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P0AFF6
- Protein
- Transcription termination/antitermination protein NusA
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 1 record with a druggable one
Structures
14 records of P0AFF6 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2JZB | Solution structure of the complex between E.coli NusA-AR2 and RNAP-aCTD | solution nmr | B | — | — |
| 2JZB | Solution structure of the complex between E.COLI nusa-AR2 and rnap- actd | solution nmr | B | — | — |
| 2KWP | Solution structure of the aminoterminal domain of E. coli NusA | solution nmr | A | — | — |
| 2KWP | Solution structure of the aminoterminal domain of E. COLI nusa | solution nmr | A | — | — |
| 5LM9 | Structure of E. coli NusA | x-ray diffraction | A | SO4, MG | — |
| 5LM9 | Structure of E. COLI nusa | x-ray diffraction | A | SO4, MG | — |
| 5MS0 | pseudo-atomic model of the RNA polymerase lambda-based antitermination complex solved by cryo-EM | electron microscopy | M | — | — |
| 5MS0 | Pseudo-atomic model of the RNA polymerase lambda-based antitermination complex solved by cryo-EM | electron microscopy | M | — | — |
| 6FLQ | CryoEM structure of E.coli RNA polymerase paused elongation complex bound to NusA | electron microscopy | F | — | 4 (best 0.69) |
| 6FLQ | Cryoem structure of E.COLI RNA polymerase paused elongation complex bound to nusa | electron microscopy | F | — | — |
| 6XAS | Cryoem structure of E. COLI rho-dependent transcription pre- termination complex | electron microscopy | G | — | — |
| 6XAV | Cryoem structure of E. COLI rho-dependent transcription pre- termination complex bound with nusg | electron microscopy | G | — | — |
| 7PY6 | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG… | electron microscopy | F | — | — |
| P0AFF6 | AlphaFold monomer V2.0 prediction for transcription TERMINATION/ANTITERMINATION protein nusa… | predicted | A | — | 2 (best 0.37) |
Ligands
Experiment against prediction
- 5LM9 chain A against the predicted model P0AFF6: TM-score 0.89, RMSD 2.61 Å
- 5LM9 chain A against the predicted model P0AFF6: TM-score 0.89, RMSD 2.61 Å
- 2JZB chain B against the predicted model P0AFF6: TM-score 0.88, RMSD 1.29 Å
- 2JZB chain B against the predicted model P0AFF6: TM-score 0.88, RMSD 1.29 Å
- 2KWP chain A against the predicted model P0AFF6: TM-score 0.85, RMSD 2.19 Å
- 2KWP chain A against the predicted model P0AFF6: TM-score 0.85, RMSD 2.19 Å
- 6FLQ chain F against the predicted model P0AFF6: TM-score 0.76, RMSD 4.47 Å
- 6FLQ chain F against the predicted model P0AFF6: TM-score 0.76, RMSD 4.47 Å
- 7PY6 chain F against the predicted model P0AFF6: TM-score 0.73, RMSD 4.79 Å
- 5MS0 chain M against the predicted model P0AFF6: TM-score 0.71, RMSD 4.31 Å
Elsewhere
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