GL1X · GenesisL1 explorer

MolNFT v1 · #277511 · protein

AlphaFold monomer V2.0 prediction for transcription TERMINATION/ANTITERMINATION protein nusa (P0AFF6)

P0AFF6: “AlphaFold monomer V2.0 prediction for transcription TERMINATION/ANTITERMINATION protein nusa (P0AFF6)”. 2 pockets (best druggability 0.37). MolNFT v1 #277511 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P0AFF6
Type
protein
Length
495 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
Molecule
Transcription TERMINATION/ANTITERMINATION protein nusa
UniProt
P0AFF6
Pockets
2 · best druggability 0.37

Structure

1 distinct chain · 48% helix, 20% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATranscription TERMINATION/ANTITERMINATION protein nusaprotein49548% helix, 20% strandP0AFF6

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1590.370.7815empty
2650.330.7614empty

Compared structures

  • 6FLQ · CryoEM structure of E.coli RNA polymerase paused elongation complex bound to NusA · an experimental structure of the same protein · chain A against F, TM-score 0.76
  • 6FLQ · Cryoem structure of E.COLI RNA polymerase paused elongation complex bound to nusa · an experimental structure of the same protein · chain A against F, TM-score 0.76
  • 7PYK · CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA… · an experimental structure of the same protein · chain A against F, TM-score 0.75
  • 7PY5 · CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (the… · an experimental structure of the same protein · chain A against F, TM-score 0.74
  • 7PY3 · CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (the consensus… · an experimental structure of the same protein · chain A against F, TM-score 0.74
  • 7PY6 · CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA… · an experimental structure of the same protein · chain A against F, TM-score 0.73
  • 7PYJ · CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA… · an experimental structure of the same protein · chain A against F, TM-score 0.73
  • 7PY7 · CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA… · an experimental structure of the same protein · chain A against F, TM-score 0.72
  • 5MS0 · pseudo-atomic model of the RNA polymerase lambda-based antitermination complex solved by… · an experimental structure of the same protein · chain A against M, TM-score 0.62
  • 5MS0 · Pseudo-atomic model of the RNA polymerase lambda-based antitermination complex solved by… · an experimental structure of the same protein · chain A against M, TM-score 0.62
  • 5LM9 · Structure of E. COLI nusa · an experimental structure of the same protein · chain A against A, TM-score 0.58
  • 5LM9 · Structure of E. coli NusA · an experimental structure of the same protein · chain A against A, TM-score 0.58

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