Research workbench
The barbed end complex of dynactin bound to BICDR1 and the cytoplasmic dynein tails (A2, B1, B2)
Analyse The barbed end complex of dynactin bound to BICDR1 and the cytoplasmic dynein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7Z8I
- Type
- protein
- Length
- 5,372 residues
- Chains
- 17
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- F2Z5G5, A0PFK5, A9XFX6, A0JNT9, Q14204, Q13409, O43237
- Ligands
- ADP, MG
Structure
electron microscopy · 12 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, D, E | — | protein | 370 | — | F2Z5G5 |
| C | — | protein | 375 | — | F2Z5G5 |
| F | — | protein | 279 | — | F2Z5G5 |
| K | — | protein | 278 | — | A0PFK5 |
| L | — | protein | 269 | — | A9XFX6 |
| X, x | — | protein | 93 | — | A0JNT9 |
| f | — | protein | 720 | — | Q14204 |
| h, o | — | protein | 358 | — | Q13409 |
| j | — | protein | 44 | — | O43237 |
| m | — | protein | 602 | — | Q14204 |
| n | — | protein | 409 | — | Q14204 |
| r | — | protein | 14 | — | O43237 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · 6 copies · chains A, B, C, D, E, F
- MG · Magnesium ion · metal · 6 copies · chains A, B, C, D, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- Q13409 · AlphaFold monomer V2.0 prediction for cytoplasmic dynein 1 intermediate chain 2 (Q13409) · a predicted model of the same protein · chain o against A, TM-score 0.99
- A0JNT9 · AlphaFold monomer V2.0 prediction for bicd family-like cargo adapter 1 (A0JNT9) · a predicted model of the same protein · chain x against A, TM-score 0.90
- O43237 · AlphaFold monomer V2.0 prediction for cytoplasmic dynein 1 light intermediate chain 2… · a predicted model of the same protein · chain r against A, TM-score 0.73
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F2Z5G5
- Every structure of UniProt A0PFK5
- Every structure of UniProt A9XFX6
- Every structure of UniProt A0JNT9
- Every structure of UniProt Q14204
- Every structure of UniProt Q13409
- Every structure of UniProt O43237
- Elsewhere: RCSB PDB 7Z8I · PDBe 7Z8I · UniProt F2Z5G5 · UniProt A0PFK5 · UniProt A9XFX6 · UniProt A0JNT9 · UniProt Q14204 · UniProt Q13409 · UniProt O43237
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.