UniProt Q14204
Cytoplasmic dynein 1 heavy chain 1 (Q14204)
Cytoplasmic dynein 1 heavy chain 1 (UniProt Q14204), EC 6.1.1.11: 19 experimental structures on GenesisL1, 7 ligands bound, 66 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q14204
- Protein
- Cytoplasmic dynein 1 heavy chain 1
- EC
- 6.1.1.11
- Experimental structures
- 19
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 66 · 4 records with a druggable one
Structures
19 records of Q14204 in the MolNFT archive: 19 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NUG | Motor domains from human cytoplasmic dynein-1 in the phi-particle conformation | electron microscopy | A, B | ADP, ATP, MG | — |
| 5OWO | Human cytoplasmic dynein N-terminus dimerization domain at 1.8 ångström resolution | x-ray diffraction | A, B, C, D | MG, CA, NA, K | — |
| 6F1T | Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1 | electron microscopy | e, f, m, n | — | — |
| 6F1U | N terminal region of dynein tail domains in complex with dynactin filament and bicdr-1 | electron microscopy | f, m, n | — | — |
| 6F1V | C terminal region of the dynein heavy chains in the dynein TAIL/DYNACTIN/BICDR1 complex | electron microscopy | f, m | — | — |
| 6F1Y | Dynein light intermediate chain region of the dynein tail/dynactin/BICDR1 complex | electron microscopy | f | — | — |
| 6F1Y | Dynein light intermediate chain region of the dynein TAIL/DYNACTIN/BICDR1 complex | electron microscopy | f | — | — |
| 6F38 | Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3 | electron microscopy | e, f, m, n | — | — |
| 6F3A | Cryo-EM structure of a single dynein tail domain bound to dynactin and BICD2N | electron microscopy | e, f | — | — |
| 7Z8G | Cytoplasmic dynein-1 motor domain | electron microscopy | A | ADP, ATP, MG, ANP | — |
| 7Z8H | Cytoplasmic dynein-1 motor domain AAA1, AAA2, and AAA3 subunits | electron microscopy | A | ADP, ATP, ANP, MG | 13 (best 0.77) |
| 7Z8H | Cytoplasmic dynein-1 motor domain AAA1, AAA2, and AAA3 subunits | electron microscopy | A | ADP, ATP, ANP, MG | — |
| 7Z8I | The barbed end complex of dynactin bound to BICDR1 and the cytoplasmic dynein tails (A2, B1, B2) | electron microscopy | f, m, n | — | — |
| 7Z8J | Cytoplasmic dynein (A2) bound to BICDR1 | electron microscopy | f, m, n | — | — |
| 7Z8K | Cytoplasmic dynein (A1) bound to BICDR1 | electron microscopy | e, f | — | — |
| 7Z8L | Cytoplasmic dynein light intermediate chain (B1) bound to the motor domain (A2). | electron microscopy | f | ADP, ATP, MG, ANP | — |
| 8FCY | Engineered human dynein motor domain in microtubule-bound state | electron microscopy | A | ADP, ATP | 20 (best 0.81) |
| 8PQV | Cytoplasmic dynein-1 motor domain in post-powerstroke state | electron microscopy | A | — | 20 (best 0.82) |
| 8PR0 | Cytoplasmic dynein-A heavy chain bound to dynactin-p150glued and IC-LC tower | electron microscopy | B, A | — | 13 (best 0.81) |
Ligands
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.