Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with minigs

Structure

electron microscopy · 5 distinct chains.

Ligands and binding sites

• K6G · [(2~{R})-2-oxidanyl-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propyl] hexadecanoate · ligand · chains R

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7WU3 · Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with miniGs · the same entry in another collection · chain R against R, TM-score 1.00
• P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
• P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain C against A, TM-score 0.92
• Q5T601 · AlphaFold monomer V2.0 prediction for adhesion G-protein coupled receptor F1 (Q5T601) · a predicted model of the same protein · chain R against A, TM-score 0.83

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P62873
• Every structure of UniProt P59768
• Every structure of UniProt Q5T601
• Elsewhere: RCSB PDB 7WU3 · PDBe 7WU3 · UniProt P62873 · UniProt P59768 · UniProt Q5T601