UniProt Q5T601
Adhesion G-protein coupled receptor F1 (Q5T601)
Adhesion G-protein coupled receptor F1 (UniProt Q5T601): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 24 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5T601
- Protein
- Adhesion G-protein coupled receptor F1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 24 · 5 records with a druggable one
Structures
9 records of Q5T601 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7WU3 | Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with minigs | electron microscopy | R | K6G | — |
| 7WU4 | Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with minigi | electron microscopy | R | CLR, K6G | — |
| 7WU5 | Cryo-EM structure of the adhesion GPCR ADGRF1(H565A/T567A) in complex with miniGi | electron microscopy | R | CLR, K6G | 5 (best 0.68) |
| 7WU5 | Cryo-EM structure of the adhesion GPCR ADGRF1(H565A/T567A) in complex with minigi | electron microscopy | R | CLR, K6G | — |
| 7WXU | GPR110/Gq complex | electron microscopy | R | — | 7 (best 0.77) |
| 7WXW | GPR110/Gs complex | electron microscopy | R | — | 5 (best 0.74) |
| 7WZ7 | GPR110/G12 complex | electron microscopy | R | — | 2 (best 0.77) |
| 7X2V | GPR110/Gi complex | electron microscopy | R | — | 5 (best 0.77) |
| Q5T601 | AlphaFold monomer V2.0 prediction for adhesion G-protein coupled receptor F1 (Q5T601) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7WZ7 chain R against the predicted model Q5T601: TM-score 0.87, RMSD 2.44 Å
- 7X2V chain R against the predicted model Q5T601: TM-score 0.86, RMSD 2.52 Å
- 7WXW chain R against the predicted model Q5T601: TM-score 0.85, RMSD 2.56 Å
- 7WXU chain R against the predicted model Q5T601: TM-score 0.85, RMSD 2.41 Å
- 7WU5 chain R against the predicted model Q5T601: TM-score 0.84, RMSD 2.38 Å
- 7WU5 chain R against the predicted model Q5T601: TM-score 0.84, RMSD 2.38 Å
- 7WU4 chain R against the predicted model Q5T601: TM-score 0.84, RMSD 2.43 Å
- 7WU3 chain R against the predicted model Q5T601: TM-score 0.83, RMSD 2.46 Å
Elsewhere
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