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Integrin ALAPHIIBBETA3 complex with crgdfv

Analyse Integrin ALAPHIIBBETA3 complex with crgdfv in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7U60
Type
protein
Length
2,711 residues
Chains
10
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P08514, P05106
Ligands
NAG, MAN, CA, MN, SO4

Structure

x-ray diffraction · 7 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein455—P08514
B—protein464—P05106
C—protein453—P08514
D—protein469—P05106
E, H—protein216——
F, L—protein214——
M, N—protein5——

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 10 copies · chains A, B, C, D
  • MAN · alpha-D-mannopyranose · sugar · 4 copies · chains A, C
  • CA · Calcium ion · metal · 8 copies · chains A, C
  • MN · Manganese (II) ion · metal · 6 copies · chains B, M, D, N
  • SO4 · Sulfate ion · ion · 8 copies · chains A, B, C, L
  • GOL · Glycerol · additive · 11 copies · chains A, B, C, D, H, L

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7U60 · Integrin alpha IIB beta3 complex with cRGDfV · the same entry in another collection · chain A against A, TM-score 1.00

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