Cryo-EM structure of deptor bound to human mtor complex 1, focussed on one protomer

Structure

electron microscopy · 4 distinct chains.

Ligands and binding sites

• IHP · Inositol hexakisphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7PEB · cryo-EM structure of DEPTOR bound to human mTOR complex 1, focussed on one protomer · the same entry in another collection · chain I against I, TM-score 1.00
• Q8N122 · AlphaFold monomer V2.0 prediction for regulatory-associated protein of mtor (Q8N122) · a predicted model of the same protein · chain E against A, TM-score 0.99
• Q9BVC4 · AlphaFold monomer V2.0 prediction for target of rapamycin complex subunit LST8 (Q9BVC4) · a predicted model of the same protein · chain C against A, TM-score 0.98
• Q8TB45 · AlphaFold monomer V2.0 prediction for dep domain-containing mtor- interacting protein… · a predicted model of the same protein · chain I against A, TM-score 0.91
• P42345 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase mtor (P42345) · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P42345
• Every structure of UniProt Q9BVC4
• Every structure of UniProt Q8N122
• Every structure of UniProt Q8TB45
• Elsewhere: RCSB PDB 7PEB · PDBe 7PEB · UniProt P42345 · UniProt Q9BVC4 · UniProt Q8N122 · UniProt Q8TB45