Crystal structure of 14-3-3 sigma in complex with 13MER amot-P130 peptide and fragment 12

Structure

x-ray diffraction · 2 distinct chains.

Ligands and binding sites

• K7Q · ~{N}-(2-azanylethyl)-2-carbamimidoyl-7-methoxy-1-benzothiophene-4-carboxamide · ligand · chains A
• CA · Calcium ion · metal · 2 copies · chains A
• MG · Magnesium ion · metal · chains A
• CL · Chloride ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7NMX · Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 12 · the same entry in another collection · chain A against A, TM-score 1.00
• P31947 · AlphaFold monomer V2.0 prediction for 14-3-3 protein sigma (P31947) · a predicted model of the same protein · chain A against A, TM-score 0.96
• Q4VCS5 · AlphaFold monomer V2.0 prediction for angiomotin (Q4VCS5) · a predicted model of the same protein · chain P against A, TM-score 0.51

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P31947
• Every structure of UniProt Q4VCS5
• Elsewhere: RCSB PDB 7NMX · PDBe 7NMX · UniProt P31947 · UniProt Q4VCS5