Research workbench
PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome
Analyse PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7KTP
- Type
- protein
- Length
- 1,544 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q92800, O75530, Q15022, Q09028
- Ligands
- ZN
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 395 | — | Q92800 |
| B | — | protein | 365 | — | O75530 |
| C | — | protein | 397 | — | Q15022 |
| D | — | protein | 387 | — | Q09028 |
Ligands and binding sites
- ZN · Zinc ion · metal · 7 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7KTP · PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome · the same entry in another collection · chain D against D, TM-score 1.00
- O75530 · AlphaFold monomer V2.0 prediction for polycomb protein eed (O75530) · a predicted model of the same protein · chain B against A, TM-score 0.98
- Q09028 · AlphaFold monomer V2.0 prediction for histone-binding protein RBBP4 (Q09028) · a predicted model of the same protein · chain D against A, TM-score 0.98
- Q92800 · AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase EZH1 (Q92800) · a predicted model of the same protein · chain A against A, TM-score 0.96
- Q15022 · AlphaFold monomer V2.0 prediction for polycomb protein SUZ12 (Q15022) · a predicted model of the same protein · chain C against A, TM-score 0.46
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92800
- Every structure of UniProt O75530
- Every structure of UniProt Q15022
- Every structure of UniProt Q09028
- Elsewhere: RCSB PDB 7KTP · PDBe 7KTP · UniProt Q92800 · UniProt O75530 · UniProt Q15022 · UniProt Q09028
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