UniProt Q09028
Histone-binding protein RBBP4 (Q09028)
Histone-binding protein RBBP4 (UniProt Q09028): 51 experimental structures on GenesisL1, 7 ligands bound, 94 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q09028
- Protein
- Histone-binding protein RBBP4
- Experimental structures
- 51
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 94 · 10 records with a druggable one
Structures
51 records of Q09028 in the MolNFT archive: 51 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XU7 | Structural basis for RbAp48 binding to FOG-1 | x-ray diffraction | A, B | — | — |
| 2XU7 | Structural basis for RBAP48 binding to fog-1 | x-ray diffraction | A, B | — | — |
| 3GFC | Crystal Structure of Histone-binding protein RBBP4 | x-ray diffraction | A | — | — |
| 3GFC | Crystal structure of histone-binding protein RBBP4 | x-ray diffraction | A | — | — |
| 4PBY | Structure of the human RbAp48-MTA1(656-686) complex | x-ray diffraction | A, B | — | — |
| 4PBY | Structure of the human RBAP48-MTA1(656-686) complex | x-ray diffraction | A, B | — | — |
| 4PBZ | Structure of the human RbAp48-MTA1(670-695) complex | x-ray diffraction | A | — | — |
| 4PBZ | Structure of the human RBAP48-MTA1(670-695) complex | x-ray diffraction | A | — | — |
| 4PC0 | Structure of the human RbAp48-MTA1(670-711) complex | x-ray diffraction | A, B | — | — |
| 4PC0 | Structure of the human RBAP48-MTA1(670-711) complex | x-ray diffraction | A, B | — | — |
| 4R7A | Crystal Structure of RBBP4 bound to PHF6 peptide | x-ray diffraction | B | — | — |
| 4R7A | Crystal structure of RBBP4 bound to PHF6 peptide | x-ray diffraction | B | — | — |
| 5FXY | Structure of the human RBBP4:MTA1(464-546) complex | x-ray diffraction | A, C, E, G | — | — |
| 5FXY | Structure of the human RBBP4:MTA1(464-546) complex | x-ray diffraction | A, C, E, G | — | — |
| 5VTB | Crystal structure of RBBP4 bound to BCL11A peptide | x-ray diffraction | A | — | — |
| 5WAI | Crystal Structure of a Suz12-Rbbp4-Jarid2-Aebp2 Heterotetrameric Complex | x-ray diffraction | A, E | — | — |
| 5WAI | Crystal structure of a SUZ12-RBBP4-JARID2-AEBP2 heterotetrameric complex | x-ray diffraction | A, E | — | — |
| 5WAK | Crystal Structure of a Suz12-Rbbp4 Binary Complex | x-ray diffraction | A | — | 9 (best 0.75) |
| 5WAK | Crystal structure of a SUZ12-RBBP4 binary complex | x-ray diffraction | A | — | — |
| 5XWR | Crystal structure of RBBP4-peptide complex | x-ray diffraction | A, B | — | — |
| 5XXQ | Crystal structure of RBBP4: ZNF827 and its function in telomere | x-ray diffraction | A, B | — | 6 (best 0.75) |
| 5XXQ | Crystal structure of RBBP4: ZNF827 and its function in telomere | x-ray diffraction | A, B | — | — |
| 5Y1U | Crystal structure of RBBP4 bound to AEBP2 rrk motif | x-ray diffraction | A, B | SO4 | — |
| 6BW3 | Crystal structure of RBBP4 in complex with PRDM3 N-terminal peptide | x-ray diffraction | C, A | UNX | — |
| 6BW4 | Crystal structure of RBBP4 in complex with PRDM16 N-terminal peptide | x-ray diffraction | C, A | UNX | — |
| 6BW4 | Crystal structure of RBBP4 in complex with PRDM16 N-terminal peptide | x-ray diffraction | C, A | UNX | — |
| 6C23 | Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Compact Active State | electron microscopy | N | — | — |
| 6C23 | Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the compact active state | electron microscopy | N | — | — |
| 6C24 | Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the extended active state | electron microscopy | N | — | — |
| 6G16 | Structure of the human RBBP4:MTA1(464-546) complex showing loop exchange | x-ray diffraction | A, C, E, G | — | 20 (best 0.82) |
| 6G16 | Structure of the human RBBP4:MTA1(464-546) complex showing loop exchange | x-ray diffraction | A, C, E, G | — | — |
| 6NQ3 | Crystal Structure of a SUZ12-RBBP4-PHF19-JARID2 Heterotetrameric Complex | x-ray diffraction | A, E | — | — |
| 6NQ3 | Crystal structure of a SUZ12-RBBP4-PHF19-JARID2 heterotetrameric complex | x-ray diffraction | A, E | — | — |
| 6WKR | PRC2-AEBP2-JARID2 bound to H2AK119UB1 nucleosome | electron microscopy | N | — | — |
| 6ZRC | Structure of the human RBAP48 in complex with a macrocyclic peptide cyclized via a xylene linker… | x-ray diffraction | A, B | ACE, PXY | — |
| 6ZRD | Structure of the human RBAP48 in complex with a macrocyclic peptide cyclized via a xylene linker… | x-ray diffraction | A, B | SEZ | — |
| 7AOA | Structure of the extended MTA1/HDAC1/MBD2/RBBP4 NURD deacetylase complex | electron microscopy | F, G | — | 6 (best 0.76) |
| 7AOA | Structure of the extended MTA1/HDAC1/MBD2/RBBP4 nurd deacetylase complex | electron microscopy | F, G | — | — |
| 7KSO | Cryo-EM structure of PRC2:EZH1-AEBP2-JARID2 | electron microscopy | D | — | — |
| 7KSR | PRC2:EZH1_A from a dimeric PRC2 bound to a nucleosome | electron microscopy | D | — | — |
| 7KTP | PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome | electron microscopy | D | — | 8 (best 0.74) |
| 7KTP | PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome | electron microscopy | D | — | — |
| 7M40 | Discovery of small molecule antagonists of human retinoblastoma binding protein 4 (RBBP4) | x-ray diffraction | A, B | YQJ | — |
| 7N40 | Crystal structure of LIN9-RBAP48-LIN37, a muvb subcomplex | x-ray diffraction | A | — | — |
| 7R1D | Structure of muvb complex | electron microscopy | A | — | — |
| 7Y5O | Crystal structure of human CAF-1 core complex in spacegroup P21 | x-ray diffraction | C, F | — | 11 (best 0.86) |
| 8IQF | Cryo-EM structure of the dimeric human CAF1-H3-H4 complex | electron microscopy | C, H | — | 11 (best 0.68) |
| 8TB9 | PRC2-J119-450 monomer bound to H1-nucleosome | electron microscopy | O | — | 8 (best 0.85) |
| 8TX8 | Crystal Structure of RBBP4 bound to ZNF512B peptide | x-ray diffraction | A, B | OXM | 6 (best 0.79) |
| 9C8U | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min | electron microscopy | D | — | 9 (best 0.86) |
| Q09028 | AlphaFold monomer V2.0 prediction for histone-binding protein RBBP4 (Q09028) | — | — | — |
Ligands
- UNX · Unknown atom or ion · in 3 records
- ACE · Acetyl group · in 1 record
- OXM · Oxamic acid · in 1 record
- PXY · Para-xylene · in 1 record
- SEZ · 1,3,5-trimethylbenzene · in 1 record
- SO4 · Sulfate ion · in 1 record
- YQJ · N~3~-{4-[3-(dimethylamino)pyrrolidin-1-yl]-6,7-dimethoxyquinazolin-2-yl}-N~1~,N~1~-dimethylpropane-1, 3-diamine · in 1 record
Elsewhere
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