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Crystal structure of psd-95 PDZ3 fused with ADAM22 C-terminal peptide

Analyse Crystal structure of psd-95 PDZ3 fused with ADAM22 C-terminal peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7CQF
Type
protein
Length
113 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Disks large homolog 4,DISINTEGRIN and metalloproteinase domain-containing protein 22
UniProt
P31016, Q9P0K1
Ligands
CHT, CL

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 31% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADisks large homolog 4,DISINTEGRIN and metalloproteinase domain-containing protein 22protein11327% helix, 31% strandP31016, Q9P0K1

Ligands and binding sites

  • CHT · Choline ion · ligand · chains A
  • CL · Chloride ion · ion · chains A
  • EDO · 1,2-ethanediol · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7CQF · Crystal structure of PSD-95 PDZ3 fused with ADAM22 C-terminal peptide · the same entry in another collection · chain A against A, TM-score 1.00
  • P31016 · AlphaFold monomer V2.0 prediction for disks large homolog 4 (P31016) · a predicted model of the same protein · chain A against A, TM-score 0.84
  • Q9P0K1 · AlphaFold monomer V2.0 prediction for disintegrin and metalloproteinase domain-containing… · a predicted model of the same protein · chain A against A, TM-score 0.31

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