MolNFT v1 · #98851 · protein
AlphaFold monomer V2.0 prediction for disks large homolog 4 (P31016)
P31016: “AlphaFold monomer V2.0 prediction for disks large homolog 4 (P31016)”. 10 pockets (best druggability 0.72). MolNFT v1 #98851 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P31016
- Type
- protein
- Length
- 724 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x43f2261C6289C306711c229D41a2680DAd1c10dC
- Molecule
- Disks large homolog 4
- UniProt
- P31016
- Pockets
- 10 · best druggability 0.72
Structure
1 distinct chain · 22% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Disks large homolog 4 | protein | 724 | 22% helix, 26% strand | P31016 |
Pockets
10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 938 | 0.72 | 0.76 | 77 | empty |
| 2 | 492 | 0.71 | 0.81 | 55 | empty |
| 3 | 139 | 0.39 | 0.74 | 26 | empty |
| 4 | 154 | 0.39 | 0.73 | 18 | empty |
| 5 | 106 | 0.37 | 0.74 | 14 | empty |
Compared structures
- 2XKX · Single particle analysis of PSD-95 in negative stain · an experimental structure of the same protein · chain A against B, TM-score 0.43
- 2XKX · Single particle analysis of psd-95 in negative stain · an experimental structure of the same protein · chain A against B, TM-score 0.43
- 1KJW · SH3-guanylate kinase module from psd-95 · an experimental structure of the same protein · chain A against A, TM-score 0.39
- 1KJW · SH3-Guanylate Kinase Module from PSD-95 · an experimental structure of the same protein · chain A against A, TM-score 0.39
- 5YPR · Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 5YPR · Crystal structure of psd-95 SH3-gk domain in complex with a synthesized inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 1JXM · Crystal structure of the gmp bound SH3-hook-gk fragment of psd-95 · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 1JXM · Crystal structure of the gmp bound SH3-hook-gk fragment of psd-95 · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 1JXO · Crystal Structure of the SH3-HOOK-GK Fragment of PSD-95 · an experimental structure of the same protein · chain A against B, TM-score 0.36
- 1JXO · Crystal structure of the SH3-hook-gk fragment of psd-95 · an experimental structure of the same protein · chain A against B, TM-score 0.36
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31016
- Elsewhere: UniProt P31016 · AlphaFold DB P31016
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