UniProt Q9P0K1
Disintegrin and metalloproteinase domain-containing protein 22 (Q9P0K1)
Disintegrin and metalloproteinase domain-containing protein 22 (UniProt Q9P0K1): 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 120 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9P0K1
- Protein
- Disintegrin and metalloproteinase domain-containing protein 22
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 120 · 7 records with a druggable one
Structures
13 records of Q9P0K1 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3G5C | Structural and biochemical studies on the ectodomain of human ADAM22 | x-ray diffraction | A, B | NAG, CA | 12 (best 0.79) |
| 3G5C | Structural and biochemical studies on the ectodomain of human ADAM22 | x-ray diffraction | A, B | — | — |
| 5Y2Z | Crystal structure of human LGI1 EPTP-ADAM22 complex | x-ray diffraction | A, C, E, G, I, K | CA | 20 (best 0.82) |
| 5Y2Z | Crystal structure of human LGI1 eptp-ADAM22 complex | x-ray diffraction | A, C, E, G, I, K | CA | — |
| 5Y31 | Crystal structure of human LGI1-ADAM22 complex | x-ray diffraction | A, C | CA, NAG | 16 (best 0.83) |
| 5Y31 | Crystal structure of human LGI1-ADAM22 complex | x-ray diffraction | A, C | CA, NAG | — |
| 7CQF | Crystal structure of PSD-95 PDZ3 fused with ADAM22 C-terminal peptide | x-ray diffraction | A | CL, CHT | — |
| 7CQF | Crystal structure of psd-95 PDZ3 fused with ADAM22 C-terminal peptide | x-ray diffraction | A | CL, CHT | — |
| 8HPY | Crystal structure of human LGI1-ADAM22 complex | x-ray diffraction | A, B | NAG, CA | 16 (best 0.79) |
| 8HQ1 | Crystal Structure Of Human Lgi1-Adam22 Complex In Space Group C2 | x-ray diffraction | A, B, C | NAG, CA | 18 (best 0.81) |
| 8HQ2 | Crystal structure of human ADAM22 in complex with human LGI1 mutant | x-ray diffraction | A, B | CA, NAG | 18 (best 0.81) |
| 8Y6B | Structure of human LGI1-ADAM22 complex in space group P212121 | x-ray diffraction | A, B, C | NAG, CA | 20 (best 0.82) |
| Q9P0K1 | AlphaFold monomer V2.0 prediction for disintegrin and metalloproteinase domain-containing protein… | predicted | A | — | — |
Ligands
Experiment against prediction
- 8HQ1 chain C against the predicted model Q9P0K1: TM-score 0.98, RMSD 1.10 Å
- 8HQ1 chain A against the predicted model Q9P0K1: TM-score 0.98, RMSD 1.10 Å
- 8HQ1 chain B against the predicted model Q9P0K1: TM-score 0.98, RMSD 1.11 Å
- 5Y2Z chain K against the predicted model Q9P0K1: TM-score 0.98, RMSD 1.13 Å
- 5Y2Z chain K against the predicted model Q9P0K1: TM-score 0.98, RMSD 1.13 Å
- 5Y2Z chain C against the predicted model Q9P0K1: TM-score 0.98, RMSD 1.12 Å
- 5Y2Z chain C against the predicted model Q9P0K1: TM-score 0.98, RMSD 1.12 Å
- 5Y2Z chain A against the predicted model Q9P0K1: TM-score 0.98, RMSD 1.14 Å
- 5Y2Z chain A against the predicted model Q9P0K1: TM-score 0.98, RMSD 1.14 Å
- 5Y31 chain A against the predicted model Q9P0K1: TM-score 0.98, RMSD 1.14 Å
Elsewhere
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