Research workbench
Structure of human BETA1 adrenergic receptor bound to carazolol
Analyse Structure of human BETA1 adrenergic receptor bound to carazolol in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7BVQ
- Type
- protein
- Length
- 906 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- D9IEF7
- Ligands
- CAU, 1WV, CLR, GLC, NA, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 455 | — | D9IEF7 |
| B | — | protein | 451 | — | D9IEF7 |
Ligands and binding sites
- CAU · (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol · ligand · 2 copies · chains A, B
- 1WV · (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate · ligand · 2 copies · chains A, B
- CLR · Cholesterol · ligand · chains A
- GLC · alpha-D-glucopyranose · sugar · 2 copies · chains B
- NA · Sodium ion · metal · chains A
- SO4 · Sulfate ion · ion · 8 copies · chains A, B
- PG4 · Tetraethylene glycol · additive · 4 copies · chains A, B
- CIT · Citric acid · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7BVQ · Structure of human beta1 adrenergic receptor bound to carazolol · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D9IEF7
- Elsewhere: RCSB PDB 7BVQ · PDBe 7BVQ · UniProt D9IEF7
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