UniProt D9IEF7
Endolysin (D9IEF7)
Endolysin (UniProt D9IEF7), EC 1.-.-.-, 1.7.-.-: 183 experimental structures on GenesisL1, 87 ligands bound, 212 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- D9IEF7
- Protein
- Endolysin
- EC
- 1.-.-.-, 1.7.-.-, 3.2.1.17
- Experimental structures
- 183
- Predicted models
- 0
- Ligands
- 87
- Pockets
- 212 · 54 records with a druggable one
Structures
183 records of D9IEF7 in the MolNFT archive: 183 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PJZ | Crystal structure of T4 lysozyme-gss-peptide in complex with teicoplanin-A2-2 | x-ray diffraction | A | — | — |
| 4PJZ | Crystal structure of T4 lysozyme-gss-peptide in complex with teicoplanin-A2-2 | x-ray diffraction | A | — | — |
| 4PK0 | Crystal structure of T4 lysozyme-peptide in complex with teicoplanin-A2-2 | x-ray diffraction | A | — | — |
| 4PK0 | Crystal structure of T4 lysozyme-peptide in complex with teicoplanin- A2-2 | x-ray diffraction | A | — | — |
| 4PLA | Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with ATP | x-ray diffraction | A | — | — |
| 4PLA | Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with ATP | x-ray diffraction | A | — | — |
| 4QKX | Structure of beta2 adrenoceptor bound to a covalent agonist and an engineered nanobody | x-ray diffraction | A | — | — |
| 4QKX | Structure of BETA2 adrenoceptor bound to a covalent agonist and an engineered nanobody | x-ray diffraction | A | — | — |
| 4S0W | Wild type T4 lysozyme structure | x-ray diffraction | A, B | — | — |
| 4S0W | Wild type T4 lysozyme structure | x-ray diffraction | A, B | — | — |
| 4U15 | M3-mT4L receptor bound to tiotropium | x-ray diffraction | A, B | — | — |
| 4U15 | M3-MT4L receptor bound to tiotropium | x-ray diffraction | A, B | — | — |
| 4U16 | M3-mT4L receptor bound to NMS | x-ray diffraction | A, B | — | — |
| 4U16 | M3-MT4L receptor bound to nms | x-ray diffraction | A, B | — | — |
| 4XSJ | Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter fused with… | x-ray diffraction | A | — | — |
| 4XSJ | Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter fused with… | x-ray diffraction | A | — | — |
| 4YC4 | Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with nucleotide analog | x-ray diffraction | A | — | — |
| 4YC4 | Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with nucleotide analog | x-ray diffraction | A | — | — |
| 5BZ6 | Crystal structure of the N-terminal domain single mutant (S92A) of the human mitochondrial calcium… | x-ray diffraction | A | SO4 | 2 (best 0.65) |
| 5BZ6 | Crystal structure of the N-terminal domain single mutant (S92A) of the human mitochondrial calcium… | x-ray diffraction | A | — | — |
| 5I0N | PI4K IIalpha bound to calcium | x-ray diffraction | A | ATP, CA | — |
| 5I0N | PI4K iialpha bound to calcium | x-ray diffraction | A | — | — |
| 5KW2 | The extra-helical binding site of GPR40 and the structural basis for allosteric agonism and… | x-ray diffraction | A | 6XQ | 4 (best 0.56) |
| 5KW2 | The extra-helical binding site of GPR40 and the structural basis for allosteric agonism and… | x-ray diffraction | A | 6XQ | — |
| 5NDD | Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with… | x-ray diffraction | A | 8TZ, NA, PO4 | 5 (best 0.81) |
| 5NDD | Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with… | x-ray diffraction | A | 8TZ, NA, PO4 | — |
| 5NDZ | Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with… | x-ray diffraction | A | 8UN, NA | — |
| 5NDZ | Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with… | x-ray diffraction | A | 8UN, NA | — |
| 5NX0 | Structure of spin-labelled T4 lysozyme mutant L115C-R119C-R1 at room temperature | x-ray diffraction | A | — | — |
| 5T1A | Structure of CC Chemokine Receptor 2 with Orthosteric and Allosteric Antagonists | x-ray diffraction | A | 73R, VT5, SO4, ZN | 6 (best 0.78) |
| 5T1A | Structure of cc chemokine receptor 2 with orthosteric and allosteric antagonists | x-ray diffraction | A | 73R, VT5, SO4, ZN | — |
| 5V7D | T4 lysozyme Y18Ymbr | x-ray diffraction | A | — | 1 (best 0.53) |
| 5V7D | T4 lysozyme Y18YMBR | x-ray diffraction | A | — | — |
| 5V7E | T4 lysozyme Y18Ymcl | x-ray diffraction | A | NA | 1 (best 0.55) |
| 5V7E | T4 lysozyme Y18YMCL | x-ray diffraction | A | NA | — |
| 5V7F | T4 lysozyme Y18Ymi | x-ray diffraction | A | — | 1 (best 0.53) |
| 5V7F | T4 lysozyme Y18YMI | x-ray diffraction | A | — | — |
| 5V83 | Structure of DCN1 bound to NAcM-HIT | x-ray diffraction | A | 8Z7 | — |
| 5V83 | Structure of DCN1 bound to nacm-hit | x-ray diffraction | A | 8Z7 | — |
| 5V86 | Structure of DCN1 bound to nacm-opt | x-ray diffraction | A | 8ZA | — |
| 5V88 | Structure of DCN1 bound to NAcM-COV | x-ray diffraction | A | 8ZD | 4 (best 0.60) |
| 5V88 | Structure of DCN1 bound to nacm-cov | x-ray diffraction | A | 8ZD | — |
| 5VBA | Structure of ESPG1 chaperone from the type VII (esx-1) secretion system determined with the… | x-ray diffraction | A, B | CL | — |
| 5VNQ | Neutron crystallographic structure of perdeuterated T4 lysozyme cysteine-free pseudo-wild type at… | neutron diffraction | A | CL | 1 (best 0.57) |
| 5VNQ | Neutron crystallographic structure of perdeuterated T4 lysozyme cysteine-free pseudo-wild type at… | neutron diffraction | A | CL | — |
| 5VNR | X-ray structure of perdeuterated T4 lysozyme cysteine-free pseudo-wild type at cryogenic temperature | x-ray diffraction | A | PO4, NA, CL | — |
| 5VNR | X-ray structure of perdeuterated T4 lysozyme cysteine-free pseudo-wild type at cryogenic temperature | x-ray diffraction | A | PO4, NA, CL | — |
| 5X7D | Structure of BETA2 adrenoceptor bound to carazolol and an intracellular allosteric antagonist | x-ray diffraction | A | CLR, CAU, ACM | — |
| 5XEZ | Structure of the Full-length glucagon class B G protein-coupled receptor | x-ray diffraction | A, B | NAG, 97V | 12 (best 0.78) |
| 5XEZ | Structure of the full-length glucagon class B G protein-coupled receptor | x-ray diffraction | A, B | NAG, 97V | — |
| 5XF1 | Structure of the Full-length glucagon class B G protein-coupled receptor | x-ray diffraction | A, B | NAG, 97V | — |
| 5XF1 | Structure of the full-length glucagon class B G protein-coupled receptor | x-ray diffraction | A, B | NAG, 97V | — |
| 5XPE | Neutron structure of the T26H mutant of T4 lysozyme | x-ray diffraction, neutron diffraction | A | NA, CL | 1 (best 0.50) |
| 5XPE | Neutron structure of the T26H mutant of T4 lysozyme | x-ray diffraction; neutron diffraction | A | NA, CL | — |
| 5XPF | High-resolution X-ray structure of the T26H mutant of T4 lysozyme | x-ray diffraction | A | NA, CL | 1 (best 0.50) |
| 5XPF | High-resolution X-ray structure of the T26H mutant of T4 lysozyme | x-ray diffraction | A | NA, CL | — |
| 5YQZ | Structure of the glucagon receptor in complex with a glucagon analogue | x-ray diffraction | R | NAG, PO4 | — |
| 5ZBH | The Crystal Structure of Human Neuropeptide Y Y1 Receptor with BMS-193885 | x-ray diffraction | A | 9AF | 5 (best 0.83) |
| 5ZBH | The crystal structure of human neuropeptide Y Y1 receptor with bms- 193885 | x-ray diffraction | A | 9AF | — |
| 5ZHP | M3 muscarinic acetylcholine receptor in complex with a selective antagonist | x-ray diffraction | A, B | GLC, 9EC | — |
123 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 31 records
- CL · Chloride ion · in 27 records
- OLA · Oleic acid · in 25 records
- NA · Sodium ion · in 24 records
- CLR · Cholesterol · in 22 records
- PO4 · Phosphate ion · in 10 records
- MHA · (carbamoylmethyl-carboxymethyl-amino)-acetic acid · in 8 records
- GLC · alpha-D-glucopyranose · in 6 records
- L6T · alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside · in 6 records
- 1WV · (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate · in 5 records
- JTZ · (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol · in 5 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 5 records
- 97V · 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl) phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl) benzamide · in 4 records
- EFK · oxidanyl(oxidanylidene)molybdenum · in 4 records
- MG · Magnesium ion · in 4 records
- MTE · Phosphonic acidmono-(2-amino-5,6-dimercapto-4-oxo-3,7,8A,9,10,10A-hexahydro-4H-8-oxa-1,3,9,10-tetraaza-anthracen-7-ylmethyl)ester · in 4 records
- ACM · Acetamide · in 3 records
- CAU · (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol · in 3 records
- MTN · S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate · in 3 records
- TIM · (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol · in 3 records
- ZN · Zinc ion · in 3 records
- 08Y · bromoergocryptine · in 2 records
- 0HK · (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane · in 2 records
- 3RX · N-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-N'-[(1R,3S,5R, 7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]ethane-1,2-diamine · in 2 records
- 480 · (2S)-2,3-dihydroxypropyl octanoate · in 2 records
- 6XQ · (3~{S})-3-cyclopropyl-3-[2-[1-[2-[2,2-dimethylpropyl-(6-methylpyridin-2-yl)carbamoyl]-5-methoxy-phenyl]piperidin-4-yl]-1-benzofuran-6-yl]propanoic acid · in 2 records
- 73R · (3S)-1-{(1S,2R,4R)-4-[methyl(propan-2-yl)amino]-2-propylcyclohexyl}-3-{[6-(trifluoromethyl)quinazolin-4-yl]amino}pyrrolidin-2-one · in 2 records
- 8NU · 3-[2-[4-(6-fluoranyl-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one · in 2 records
- 8TZ · (~{S})-(4-fluoranyl-2-propyl-phenyl)-(1~{H}-imidazol-2-yl)methanol · in 2 records
- 8UN · 2-(6-bromanyl-1,3-benzodioxol-5-yl)-~{N}-(4-cyanophenyl)-1-[(1~{S})-1-cyclohexylethyl]benzimidazole-5-carboxamide · in 2 records
Experiment against prediction
- 6VMS chain R against the predicted model P14416: TM-score 0.88, RMSD 2.78 Å
- 6VMS chain R against the predicted model P14416: TM-score 0.88, RMSD 2.78 Å
- 5NDD chain A against the predicted model P0ABE7: TM-score 0.20, RMSD 1.86 Å
- 5NDD chain A against the predicted model P0ABE7: TM-score 0.20, RMSD 1.86 Å
- 5NDZ chain A against the predicted model P0ABE7: TM-score 0.20, RMSD 1.87 Å
- 5NDZ chain A against the predicted model P0ABE7: TM-score 0.20, RMSD 1.87 Å
- 6P5V chain A against the predicted model Q96GG9: TM-score 0.58, RMSD 3.10 Å
- 6P5V chain A against the predicted model Q96GG9: TM-score 0.58, RMSD 3.10 Å
- 6P5W chain A against the predicted model Q96GG9: TM-score 0.58, RMSD 2.95 Å
- 5ZTY chain A against the predicted model P34972: TM-score 0.65, RMSD 1.60 Å
Elsewhere
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