Bacterial oligosaccharyltransferase pglb in complex with an inhibitory peptide and a reactive lipid-linked oligosaccharide analog

Structure

x-ray diffraction · 2 distinct chains.

Ligands and binding sites

• FFK · [(2~{R},3~{R},4~{R},5~{S},6~{R})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl] [oxidanyl-[(2~{Z},6~{Z},10~{Z})-3,7,11,15-tetramethylhexadeca-2, 6,10,14-tetraenoxy]phosphoryl] hydrogen phosphate · ligand · chains A, B
• MN · Manganese (II) ion · metal · 2 copies · chains A
• NA · Sodium ion · metal · chains A
• MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains A
• PEG · Di(hydroxyethyl)ether · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6GXC · Bacterial oligosaccharyltransferase PglB in complex with an inhibitory peptide and a… · the same entry in another collection · chain A against A, TM-score 1.00
• B9KDD4 · AlphaFold monomer V2.0 prediction for undecaprenyl- diphosphooligosaccharide--protein… · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt B9KDD4
• Elsewhere: RCSB PDB 6GXC · PDBe 6GXC · UniProt B9KDD4