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Ligand · FFK

FFK · [(2~{R},3~{R},4~{R},5~{S},6~{R})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl] [oxidanyl-[(2~{Z},6~{Z},10~{Z})-3,7,11,15-tetramethylhexadeca-2, 6,10,14-tetraenoxy]phosphoryl] hydrogen phosphate

FFK, [(2~{R},3~{R},4~{R},5~{S},6~{R})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl] [oxidanyl-[(2~{Z},6~{Z},10~{Z})-3,7,11,15-tetramethylhexadeca-2, 6,10,14-tetraenoxy]phosphoryl] hydrogen phosphate (C28 H49 N O12 P2, 653.6…

Component
FFK
Formula
C28 H49 N O12 P2
Class
ligand
Structures
2
PDB entries
1

Binding sites

FFK in 2 structures; the first of them:

  • 6GXC · Bacterial oligosaccharyltransferase PglB in complex with an inhibitory peptide and a… · FFK A806 · binds ASP56, ALA59, PHE60, TYR79, TYR196, SER198, SER201, ALA205 and 13 more
  • 6GXC · Bacterial oligosaccharyltransferase pglb in complex with an inhibitory peptide and a… · FFK A806 · binds ASP56, ALA59, PHE60, TYR79, TYR196, SER198, SER201, ALA205 and 13 more

Residues it binds most

TYR 2, ALA 2, GLY 2, PHE 2, SER 2, ARG 2, ASP 2, DAB 2, GLN 2, LEU 2 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion
  • NA · Sodium ion
  • MES · 2-(N-morpholino)-ethanesulfonic acid
  • PEG · Di(hydroxyethyl)ether

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