Research workbench
Crystal structure of the human WNK2 cct-like 1 domain in complex with a WNK1 rfxv peptide
Analyse Crystal structure of the human WNK2 cct-like 1 domain in complex with a WNK1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6FBK
- Type
- protein
- Length
- 100 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SERINE/THREONINE-protein kinase WNK2; SERINE/THREONINE-protein kinase WNK1
- EC
- 2.7.11.1
- UniProt
- Q9Y3S1, Q9H4A3
Structure
x-ray diffraction · 2 distinct chains · 26% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase WNK2 (EC 2.7.11.1) | protein | 83 | 31% helix, 24% strand | Q9Y3S1 |
| P | SERINE/THREONINE-protein kinase WNK1 (EC 2.7.11.1) | protein | 17 | 0% helix, 53% strand | Q9H4A3 |
Interfaces
1 interface between chains.
- A–P · 577 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 6FBK · Crystal structure of the human WNK2 CCT-like 1 domain in complex with a WNK1 RFXV peptide · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Y3S1 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase WNK2 (Q9Y3S1) · a predicted model of the same protein · chain A against A, TM-score 0.91
- Q9H4A3 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase WNK1 (Q9H4A3) · a predicted model of the same protein · chain P against A, TM-score 0.45
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y3S1
- Every structure of UniProt Q9H4A3
- Elsewhere: RCSB PDB 6FBK · PDBe 6FBK · UniProt Q9Y3S1 · UniProt Q9H4A3
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