UniProt Q9Y3S1
Serine/threonine-protein kinase WNK2 (Q9Y3S1)
Serine/threonine-protein kinase WNK2 (UniProt Q9Y3S1), EC 2.7.11.1: 3 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y3S1
- Protein
- Serine/threonine-protein kinase WNK2
- EC
- 2.7.11.1
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
4 records of Q9Y3S1 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ELM | Crystal structure of the human WNK2 CCT1 domain | x-ray diffraction | A | — | 2 (best 0.34) |
| 6ELM | Crystal structure of the human WNK2 CCT1 domain | x-ray diffraction | A | — | — |
| 6FBK | Crystal structure of the human WNK2 cct-like 1 domain in complex with a WNK1 rfxv peptide | x-ray diffraction | A | — | — |
| Q9Y3S1 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase WNK2 (Q9Y3S1) | predicted | A | — | 5 (best 0.77) |
Experiment against prediction
- 6ELM chain A against the predicted model Q9Y3S1: TM-score 0.92, RMSD 1.34 Å
- 6ELM chain A against the predicted model Q9Y3S1: TM-score 0.92, RMSD 1.34 Å
- 6FBK chain A against the predicted model Q9Y3S1: TM-score 0.91, RMSD 1.13 Å
Elsewhere
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