Research workbench
Mycobacterium tuberculosis rnap promoter unwinding intermediate complex with RBPA/CARD and AP3 promoter captured by corallopyronin
Analyse Mycobacterium tuberculosis rnap promoter unwinding intermediate complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6EEC
- Type
- protein + DNA
- Length
- 3,636 residues
- Chains
- 10
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A5U8D3, V9Z879, A5U053, A0A0T9N9K3, P9WGI0, P9WHJ4, P9WJG2
- Ligands
- C0L, ZN, MG
Structure
electron microscopy · 10 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 225 | — | A5U8D3 |
| B | — | protein | 237 | — | A5U8D3 |
| C | — | protein | 1111 | — | V9Z879 |
| D | — | protein | 1266 | — | A5U053 |
| E | — | protein | 83 | — | A0A0T9N9K3 |
| F | — | protein | 319 | — | P9WGI0 |
| J | — | protein | 108 | — | P9WHJ4 |
| O | — | dna | 65 | — | — |
| P | — | dna | 63 | — | — |
| M | — | protein | 159 | — | P9WJG2 |
Ligands and binding sites
- C0L · Methyl [(1E,5R)-5-{(3E)-3-[(2E,4E,8R,9E,12E)-1,8-dihydroxy-2,5,9-trimethyltetradeca-2,4,9,12-tetraen-1-ylidene]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hex-1-en-1-yl]carbamate · ligand · chains C, D
- ZN · Zinc ion · metal · 2 copies · chains D
- MG · Magnesium ion · metal · chains D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6EEC · Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD… · the same entry in another collection · chain M against M, TM-score 1.00
- A5U053 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (A5U053) · a predicted model of the same protein · chain D against A, TM-score 0.95
- P9WJG2 · AlphaFold monomer V2.0 prediction for RNA polymerase-binding transcription factor card… · a predicted model of the same protein · chain M against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5U8D3
- Every structure of UniProt V9Z879
- Every structure of UniProt A5U053
- Every structure of UniProt A0A0T9N9K3
- Every structure of UniProt P9WGI0
- Every structure of UniProt P9WHJ4
- Every structure of UniProt P9WJG2
- Elsewhere: RCSB PDB 6EEC · PDBe 6EEC · UniProt A5U8D3 · UniProt V9Z879 · UniProt A5U053 · UniProt A0A0T9N9K3 · UniProt P9WGI0 · UniProt P9WHJ4 · UniProt P9WJG2
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