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UniProt P9WJG2

RNA polymerase-binding transcription factor CarD (P9WJG2)

RNA polymerase-binding transcription factor CarD (UniProt P9WJG2): 20 experimental structures and 1 predicted model on GenesisL1, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P9WJG2
Protein
RNA polymerase-binding transcription factor CarD
Experimental structures
20
Predicted models
1
Pockets
27 · 19 records with a druggable one

Structures

21 records of P9WJG2 in the MolNFT archive: 20 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6EDTMycobacterium tuberculosis RNAP open promoter complex with RbpA/CarD and AP3 promoterelectron microscopyM—1 (best 0.86)
6EDTMycobacterium tuberculosis rnap open promoter complex with RBPA/CARD and AP3 promoterelectron microscopyM—1 (best 0.86)
6EE8Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3…electron microscopyM—1 (best 0.79)
6EE8Mycobacterium tuberculosis rnap promoter unwinding intermediate complex with RBPA/CARD and AP3…electron microscopyM—1 (best 0.79)
6EECMycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3…electron microscopyM—1 (best 0.82)
6EECMycobacterium tuberculosis rnap promoter unwinding intermediate complex with RBPA/CARD and AP3…electron microscopyM—1 (best 0.82)
6VVXMycobacterium tuberculosis WT RNAP transcription initiation intermediate structure with Sorangicinelectron microscopyM—2 (best 0.78)
6VVXMycobacterium tuberculosis wt rnap transcription initiation intermediate structure with sorangicinelectron microscopyM—2 (best 0.78)
6VVYMycobacterium tuberculosis WT RNAP transcription open promoter complex with Sorangicinelectron microscopyM—1 (best 0.79)
6VVYMycobacterium tuberculosis wt rnap transcription open promoter complex with sorangicinelectron microscopyM—1 (best 0.79)
6VVZMycobacterium tuberculosis RNAP S456L mutant transcription initiation intermediate structure with…electron microscopyM—1 (best 0.81)
6VVZMycobacterium tuberculosis rnap S456L mutant transcription initiation intermediate structure with…electron microscopyM—1 (best 0.81)
6VW0Mycobacterium tuberculosis RNAP S456L mutant open promoter complexelectron microscopyM—2 (best 0.85)
6VW0Mycobacterium tuberculosis rnap S456L mutant open promoter complexelectron microscopyM—2 (best 0.85)
7KIFMycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription…electron microscopyM—2 (best 0.72)
7KIFMycobacterium tuberculosis wt rnap transcription open promoter complex with WHIB7 transcription…electron microscopyM—2 (best 0.72)
7KIMMycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription…electron microscopyM——
7KIMMycobacterium tuberculosis wt rnap transcription closed promoter complex with WHIB7 transcription…electron microscopyM——
7KINMycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoterelectron microscopyM—2 (best 0.82)
7KINMycobacterium tuberculosis wt rnap transcription open promoter complex with WHIB7 promoterelectron microscopyM—2 (best 0.82)
P9WJG2AlphaFold monomer V2.0 prediction for RNA polymerase-binding transcription factor card (P9WJG2)predictedA—1 (best 0.51)

Experiment against prediction

Elsewhere

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