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MolNFT v1 · #147461 · protein + DNA

Mycobacterium tuberculosis rnap open promoter complex with RBPA/CARD and AP3 promoter

6EDT: “Mycobacterium tuberculosis rnap open promoter complex with RBPA/CARD and AP3 promoter”. Electron microscopy, 2 ligands (ZN, MG). MolNFT v1 #147461 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6EDT
Type
protein + DNA
Length
3,646 residues
Chains
10
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A5U8D3, V9Z879, A5U053, A0A0T9N9K3, P9WGI0, P9WHJ4, P9WJG2
Ligands
ZN, MG

Structure

electron microscopy · 10 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein225—A5U8D3
B—protein237—A5U8D3
C—protein1111—V9Z879
D—protein1270—A5U053
E—protein83—A0A0T9N9K3
F—protein322—P9WGI0
J—protein109—P9WHJ4
O—dna65——
P—dna65——
M—protein159—P9WJG2

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains D
  • MG · Magnesium ion · metal · chains D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6EDT · Mycobacterium tuberculosis RNAP open promoter complex with RbpA/CarD and AP3 promoter · the same entry in another collection · chain M against M, TM-score 1.00
  • P9WJG2 · AlphaFold monomer V2.0 prediction for RNA polymerase-binding transcription factor card… · a predicted model of the same protein · chain M against A, TM-score 0.94
  • A5U053 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (A5U053) · a predicted model of the same protein · chain D against A, TM-score 0.94

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