UniProt P9WGI0
RNA polymerase sigma factor SigA (P9WGI0)
RNA polymerase sigma factor SigA (UniProt P9WGI0): 18 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 60 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WGI0
- Protein
- RNA polymerase sigma factor SigA
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 60 · 8 records with a druggable one
Structures
19 records of P9WGI0 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4X8K | Mycobacterium tuberculosis RbpA-SID in complex with SigmaA domain 2 | x-ray diffraction | A | SO4 | — |
| 4X8K | Mycobacterium tuberculosis rbpa-sid in complex with sigmaa domain 2 | x-ray diffraction | A | — | — |
| 6EDT | Mycobacterium tuberculosis RNAP open promoter complex with RbpA/CarD and AP3 promoter | electron microscopy | F | — | 6 (best 0.86) |
| 6EDT | Mycobacterium tuberculosis rnap open promoter complex with RBPA/CARD and AP3 promoter | electron microscopy | F | — | — |
| 6EE8 | Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3… | electron microscopy | F | — | 8 (best 0.79) |
| 6EE8 | Mycobacterium tuberculosis rnap promoter unwinding intermediate complex with RBPA/CARD and AP3… | electron microscopy | F | — | — |
| 6EEC | Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3… | electron microscopy | F | — | 8 (best 0.86) |
| 6EEC | Mycobacterium tuberculosis rnap promoter unwinding intermediate complex with RBPA/CARD and AP3… | electron microscopy | F | — | — |
| 6M7J | Mycobacterium tuberculosis RNAP with RbpA/us fork and Corallopyronin | electron microscopy | F | — | — |
| 6M7J | Mycobacterium tuberculosis rnap with RBPA/US fork and corallopyronin | electron microscopy | F | — | — |
| 6VVX | Mycobacterium tuberculosis WT RNAP transcription initiation intermediate structure with Sorangicin | electron microscopy | F | SRN | 10 (best 0.81) |
| 6VVX | Mycobacterium tuberculosis wt rnap transcription initiation intermediate structure with sorangicin | electron microscopy | F | — | — |
| 6VVY | Mycobacterium tuberculosis WT RNAP transcription open promoter complex with Sorangicin | electron microscopy | F | SRN | 7 (best 0.86) |
| 6VVY | Mycobacterium tuberculosis wt rnap transcription open promoter complex with sorangicin | electron microscopy | F | SRN | — |
| 6VVZ | Mycobacterium tuberculosis RNAP S456L mutant transcription initiation intermediate structure with… | electron microscopy | F | — | 8 (best 0.81) |
| 6VVZ | Mycobacterium tuberculosis rnap S456L mutant transcription initiation intermediate structure with… | electron microscopy | F | — | — |
| 6VW0 | Mycobacterium tuberculosis RNAP S456L mutant open promoter complex | electron microscopy | F | — | 9 (best 0.85) |
| 6VW0 | Mycobacterium tuberculosis rnap S456L mutant open promoter complex | electron microscopy | F | — | — |
| P9WGI0 | AlphaFold monomer V2.0 prediction for RNA polymerase sigma factor siga (P9WGI0) | predicted | A | — | 4 (best 0.78) |
Ligands
Experiment against prediction
- 4X8K chain A against the predicted model P9WGI0: TM-score 0.98, RMSD 0.65 Å
- 4X8K chain A against the predicted model P9WGI0: TM-score 0.98, RMSD 0.65 Å
- 6EE8 chain F against the predicted model P9WGI0: TM-score 0.92, RMSD 1.67 Å
- 6EE8 chain F against the predicted model P9WGI0: TM-score 0.92, RMSD 1.67 Å
- 6VVX chain F against the predicted model P9WGI0: TM-score 0.92, RMSD 1.44 Å
- 6VVX chain F against the predicted model P9WGI0: TM-score 0.92, RMSD 1.44 Å
- 6VVZ chain F against the predicted model P9WGI0: TM-score 0.91, RMSD 1.78 Å
- 6VVZ chain F against the predicted model P9WGI0: TM-score 0.91, RMSD 1.78 Å
- 6EEC chain F against the predicted model P9WGI0: TM-score 0.91, RMSD 1.54 Å
- 6EEC chain F against the predicted model P9WGI0: TM-score 0.91, RMSD 1.54 Å
Elsewhere
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