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MolNFT v1 · #179876 · protein + DNA

Mycobacterium tuberculosis wt rnap transcription open promoter complex with WHIB7 promoter

7KIN: “Mycobacterium tuberculosis wt rnap transcription open promoter complex with WHIB7 promoter”. Electron microscopy, 2 ligands (ZN, MG). MolNFT v1 #179876 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7KIN
Type
protein + DNA
Length
3,612 residues
Chains
10
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A5U8D3, A5U052, A0A045J9E2, A0A0T9N9K3, A0A0H3LGM9, P9WHJ4, P9WJG2
Ligands
ZN, MG

Structure

electron microscopy · 10 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein225—A5U8D3
B—protein237—A5U8D3
C—protein1111—A5U052
D—protein1270—A0A045J9E2
E—protein83—A0A0T9N9K3
F—protein317—A0A0H3LGM9
J—protein107—P9WHJ4
M—protein159—P9WJG2
O—dna54——
P—dna49——

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains D
  • MG · Magnesium ion · metal · chains D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7KIN · Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter · the same entry in another collection · chain P against P, TM-score 1.00
  • A5U052 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (A5U052) · a predicted model of the same protein · chain C against A, TM-score 0.99
  • A5U8D3 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (A5U8D3) · a predicted model of the same protein · chain A against A, TM-score 0.94

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