Research workbench
The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant
Analyse The crystal structure of the nucleosome containing a cancer-associated histone… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5Z30
- Type
- protein + DNA
- Length
- 1,047 residues
- Chains
- 10
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P68431, P62805, P0C0S5, P06899
- Ligands
- MN, CL
Structure
x-ray diffraction · 9 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 96 | — | P68431 |
| B | — | protein | 77 | — | P62805 |
| C | — | protein | 105 | — | P0C0S5 |
| D | — | protein | 93 | — | P06899 |
| E | — | protein | 99 | — | P68431 |
| F | — | protein | 84 | — | P62805 |
| G | — | protein | 110 | — | P0C0S5 |
| H | — | protein | 91 | — | P06899 |
| I, J | — | dna | 146 | — | — |
Ligands and binding sites
- MN · Manganese (II) ion · metal · 11 copies · chains E, I, J
- CL · Chloride ion · ion · 2 copies · chains A, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5Z30 · The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C… · the same entry in another collection · chain J against J, TM-score 1.00
- P0C0S5 · AlphaFold monomer V2.0 prediction for histone H2A.Z (P0C0S5) · a predicted model of the same protein · chain C against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P68431
- Every structure of UniProt P62805
- Every structure of UniProt P0C0S5
- Every structure of UniProt P06899
- Elsewhere: RCSB PDB 5Z30 · PDBe 5Z30 · UniProt P68431 · UniProt P62805 · UniProt P0C0S5 · UniProt P06899
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