UniProt P0C0S5
Histone H2A.Z (P0C0S5)
Histone H2A.Z (UniProt P0C0S5): 25 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 52 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0C0S5
- Protein
- Histone H2A.Z
- Experimental structures
- 25
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 52 · 5 records with a druggable one
Structures
26 records of P0C0S5 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3WA9 | The nucleosome containing human H2A.Z.1 | x-ray diffraction | C, G | — | — |
| 3WA9 | The nucleosome containing human H2A.Z.1 | x-ray diffraction | C, G | — | — |
| 4CAY | Crystal structure of a human Anp32e-H2A.Z-H2B complex | x-ray diffraction | A | — | — |
| 4CAY | Crystal structure of a human ANP32E-H2A.Z-H2B complex | x-ray diffraction | A | — | — |
| 4NFT | Crystal structure of human lnkH2B-h2A.Z-Anp32e | x-ray diffraction | A, B, C, D | — | — |
| 4NFT | Crystal structure of human LNKH2B-H2A.Z-ANP32E | x-ray diffraction | A, B, C, D | — | — |
| 5B31 | The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1. | x-ray diffraction | G | — | — |
| 5B31 | The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1. | x-ray diffraction | G | — | — |
| 5B32 | The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.3. | x-ray diffraction | G | CL | 7 (best 0.82) |
| 5B32 | The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.3. | x-ray diffraction | G | — | — |
| 5B33 | The crystal structure of the H2AZ nucleosome with H3.3. | x-ray diffraction | C, G | — | — |
| 5B33 | The crystal structure of the H2AZ nucleosome with H3.3. | x-ray diffraction | C, G | — | — |
| 5CHL | Structural basis of H2A.Z recognition by YL1 histone chaperone component of SRCAP/SWR1 chromatin… | x-ray diffraction | B | — | 1 (best 0.37) |
| 5CHL | Structural basis of H2A.Z recognition by YL1 histone chaperone component of SRCAP/SWR1 chromatin… | x-ray diffraction | B | — | — |
| 5FUG | Crystal structure of a human YL1-H2A.Z-H2B complex | x-ray diffraction | A, D, G, J | — | — |
| 5FUG | Crystal structure of a human YL1-H2A.Z-H2B complex | x-ray diffraction | A, D, G, J | — | — |
| 5Z30 | The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant | x-ray diffraction | C, G | — | 12 (best 0.79) |
| 5Z30 | The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant | x-ray diffraction | C, G | — | — |
| 6JOU | Crystal structure of the human nucleosome containing H2A.Z.1 S42R | x-ray diffraction | C, G | — | — |
| 6JOU | Crystal structure of the human nucleosome containing H2A.Z.1 S42R | x-ray diffraction | C, G | — | — |
| 7YRD | histone methyltransferase | electron microscopy | C, G | — | 11 (best 0.79) |
| 7YRG | histone methyltransferase | electron microscopy | C, G | — | — |
| 8JHF | Native SUV420H1 bound to 167-bp nucleosome | electron microscopy | C, G | — | 11 (best 0.76) |
| 8T9F | Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1 | electron microscopy | G, C | — | 10 (best 0.80) |
| 9C62 | P400 subcomplex of the native human TIP60 complex | electron microscopy | N | — | — |
| P0C0S5 | AlphaFold monomer V2.0 prediction for histone H2A.Z (P0C0S5) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 1 record
Experiment against prediction
- 5B33 chain G against the predicted model P0C0S5: TM-score 0.99, RMSD 0.39 Å
- 5B33 chain G against the predicted model P0C0S5: TM-score 0.99, RMSD 0.39 Å
- 6JOU chain G against the predicted model P0C0S5: TM-score 0.99, RMSD 0.41 Å
- 6JOU chain G against the predicted model P0C0S5: TM-score 0.99, RMSD 0.41 Å
- 5B33 chain C against the predicted model P0C0S5: TM-score 0.99, RMSD 0.44 Å
- 5B33 chain C against the predicted model P0C0S5: TM-score 0.99, RMSD 0.44 Å
- 3WA9 chain G against the predicted model P0C0S5: TM-score 0.99, RMSD 0.44 Å
- 3WA9 chain G against the predicted model P0C0S5: TM-score 0.99, RMSD 0.44 Å
- 6JOU chain C against the predicted model P0C0S5: TM-score 0.99, RMSD 0.45 Å
- 6JOU chain C against the predicted model P0C0S5: TM-score 0.99, RMSD 0.45 Å
Elsewhere
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