UniProt P68431
Histone H3.1 (P68431)
Histone H3.1 (UniProt P68431): 425 experimental structures and 1 predicted model on GenesisL1, 13 ligands bound, 1,354 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P68431
- Protein
- Histone H3.1
- Experimental structures
- 425
- Predicted models
- 1
- Ligands
- 13
- Pockets
- 1,354 · 134 records with a druggable one
Structures
426 records of P68431 in the MolNFT archive: 425 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2B2T | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and… | x-ray diffraction | D | — | — |
| 2B2T | Tandem chromodomains of human CHD1 complexed with histone H3 tail containing trimethyllysine 4 and… | x-ray diffraction | D | — | — |
| 2B2U | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and… | x-ray diffraction | D | — | — |
| 2B2U | Tandem chromodomains of human CHD1 complexed with histone H3 tail containing trimethyllysine 4 and… | x-ray diffraction | D | — | — |
| 2B2V | Crystal structure analysis of human CHD1 chromodomains 1 and 2 bound to histone H3 resi 1-15 MeK4 | x-ray diffraction | D | — | — |
| 2B2V | Crystal structure analysis of human CHD1 chromodomains 1 and 2 bound to histone H3 resi 1-15 MEK4 | x-ray diffraction | D | — | — |
| 2B2W | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 | x-ray diffraction | D | — | — |
| 2B2W | Tandem chromodomains of human CHD1 complexed with histone H3 tail containing trimethyllysine 4 | x-ray diffraction | D | — | — |
| 2CV5 | Crystal structure of human nucleosome core particle | x-ray diffraction | A, E | — | — |
| 2CV5 | Crystal structure of human nucleosome core particle | x-ray diffraction | A, E | — | — |
| 2L75 | Solution structure of CHD4-PHD2 in complex with H3K9me3 | solution nmr | B | — | — |
| 2L75 | Solution structure of CHD4-PHD2 in complex with H3K9ME3 | solution nmr | B | — | — |
| 2RI7 | Crystal structure of PHD finger-linker-bromodomain Y17E mutant from human BPTF in the H3(1-9)K4ME2… | x-ray diffraction | P | — | — |
| 2RI7 | Crystal structure of phd finger-linker-bromodomain Y17E mutant from human bptf in the H3(1-9)K4ME2… | x-ray diffraction | P | — | — |
| 2UXN | Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation | x-ray diffraction | E | — | — |
| 2UXN | Structural basis of histone demethylation by LSD1 revealed by suicide inactivation | x-ray diffraction | E | — | — |
| 3A1B | Crystal structure of the DNMT3A ADD domain in complex with histone H3 | x-ray diffraction | A | — | — |
| 3A1B | Crystal structure of the DNMT3A add domain in complex with histone H3 | x-ray diffraction | A | — | — |
| 3AFA | The human nucleosome structure | x-ray diffraction | A, E | — | — |
| 3AFA | The human nucleosome structure | x-ray diffraction | A, E | — | — |
| 3AYW | Crystal Structure of Human Nucleosome Core Particle Containing H3K56Q mutation | x-ray diffraction | A, E | — | — |
| 3AYW | Crystal structure of human nucleosome core particle containing H3K56Q mutation | x-ray diffraction | A, E | — | — |
| 3AZE | Crystal Structure of Human Nucleosome Core Particle Containing H3K64Q mutation | x-ray diffraction | A, E | — | — |
| 3AZE | Crystal structure of human nucleosome core particle containing H3K64Q mutation | x-ray diffraction | A, E | — | — |
| 3AZF | Crystal Structure of Human Nucleosome Core Particle Containing H3K79Q mutation | x-ray diffraction | A, E | — | — |
| 3AZF | Crystal structure of human nucleosome core particle containing H3K79Q mutation | x-ray diffraction | A, E | — | — |
| 3AZG | Crystal Structure of Human Nucleosome Core Particle Containing H3K115Q mutation | x-ray diffraction | A, E | — | — |
| 3AZG | Crystal structure of human nucleosome core particle containing H3K115Q mutation | x-ray diffraction | A, E | — | — |
| 3AZH | Crystal Structure of Human Nucleosome Core Particle Containing H3K122Q mutation | x-ray diffraction | A, E | — | — |
| 3AZH | Crystal structure of human nucleosome core particle containing H3K122Q mutation | x-ray diffraction | A, E | — | — |
| 3AZI | Crystal Structure of Human Nucleosome Core Particle Containing H4K31Q mutation | x-ray diffraction | A, E | — | — |
| 3AZI | Crystal structure of human nucleosome core particle containing H4K31Q mutation | x-ray diffraction | A, E | — | — |
| 3AZJ | Crystal Structure of Human Nucleosome Core Particle Containing H4K44Q mutation | x-ray diffraction | A, E | — | — |
| 3AZJ | Crystal structure of human nucleosome core particle containing H4K44Q mutation | x-ray diffraction | A, E | — | — |
| 3AZK | Crystal Structure of Human Nucleosome Core Particle Containing H4K59Q mutation | x-ray diffraction | A, E | — | — |
| 3AZK | Crystal structure of human nucleosome core particle containing H4K59Q mutation | x-ray diffraction | A, E | — | — |
| 3AZL | Crystal Structure of Human Nucleosome Core Particle Containing H4K77Q mutation | x-ray diffraction | A, E | — | — |
| 3AZL | Crystal structure of human nucleosome core particle containing H4K77Q mutation | x-ray diffraction | A, E | — | — |
| 3AZM | Crystal Structure of Human Nucleosome Core Particle Containing H4K79Q mutation | x-ray diffraction | A, E | — | — |
| 3AZM | Crystal structure of human nucleosome core particle containing H4K79Q mutation | x-ray diffraction | A, E | — | — |
| 3AZN | Crystal Structure of Human Nucleosome Core Particle Containing H4K91Q mutation | x-ray diffraction | A, E | — | — |
| 3AZN | Crystal structure of human nucleosome core particle containing H4K91Q mutation | x-ray diffraction | A, E | — | — |
| 3KMT | Crystal structure of vSET/SAH/H3 ternary complex | x-ray diffraction | G, H, I | — | — |
| 3KMT | Crystal structure of VSET/SAH/H3 ternary complex | x-ray diffraction | G, H, I | — | — |
| 3KQI | crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide | x-ray diffraction | B | — | — |
| 3KQI | Crystal structure of PHF2 phd domain complexed with H3K4ME3 peptide | x-ray diffraction | B | — | — |
| 3LQI | Crystal structure of MLL1 PHD3-Bromo complexed with H3(1-9)K4me2 peptide | x-ray diffraction | R, S, T | — | — |
| 3LQI | Crystal structure of MLL1 PHD3-bromo complexed with H3(1-9)K4ME2 peptide | x-ray diffraction | R, S, T | — | — |
| 3LQJ | Crystal structure of MLL1 PHD3-Bromo complexed with H3(1-9)K4me3 peptide | x-ray diffraction | Q, T | — | — |
| 3LQJ | Crystal structure of MLL1 PHD3-bromo complexed with H3(1-9)K4ME3 peptide | x-ray diffraction | Q, T | — | — |
| 3O34 | Crystal structure of TRIM24 PHD-Bromo complexed with H3(13-32)K23ac peptide | x-ray diffraction | B | — | — |
| 3O34 | Crystal structure of TRIM24 phd-bromo complexed with H3(13-32)K23AC peptide | x-ray diffraction | B | — | — |
| 3O35 | Crystal structure of TRIM24 PHD-Bromo complexed with H3(23-31)K27ac peptide | x-ray diffraction | D, E | — | — |
| 3O35 | Crystal structure of TRIM24 phd-bromo complexed with H3(23-31)K27AC peptide | x-ray diffraction | D, E | — | — |
| 3O37 | Crystal structure of TRIM24 PHD-Bromo complexed with H3(1-10)K4 peptide | x-ray diffraction | E, F, G, H | — | — |
| 3O37 | Crystal structure of TRIM24 phd-bromo complexed with H3(1-10)K4 peptide | x-ray diffraction | E, F, G, H | — | — |
| 3U4S | Histone Lysine demethylase JMJD2A in complex with T11C peptide substrate crosslinked to… | x-ray diffraction | C, D | — | — |
| 3U4S | Histone lysine demethylase JMJD2A in complex with T11C peptide substrate crosslinked to… | x-ray diffraction | C, D | — | — |
| 3U5N | Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-20)K9me3K14ac histone peptide | x-ray diffraction | C, D | — | — |
| 3U5N | Crystal structure of the complex of TRIM33 phd-bromo and H3(1-20) K9ME3K14AC histone peptide | x-ray diffraction | C, D | — | — |
366 records more on the page itself.
Ligands
- MN · Manganese (II) ion · in 24 records
- CL · Chloride ion · in 16 records
- UNX · Unknown atom or ion · in 13 records
- MG · Magnesium ion · in 9 records
- ZN · Zinc ion · in 6 records
- CA · Calcium ion · in 5 records
- PTD · Pentanedial · in 5 records
- SO4 · Sulfate ion · in 3 records
- AU · Gold ion · in 2 records
- SAH · S-adenosyl-L-homocysteine · in 2 records
- XIS · 4-diphenylphosphanylbenzoic acid · in 2 records
- NH2 · Amino group · in 1 record
- SAM · S-adenosylmethionine · in 1 record
Experiment against prediction
- 5XFR chain C against the predicted model P68431: TM-score 1.00, RMSD 0.02 Å
- 6KVD chain A against the predicted model P68431: TM-score 0.99, RMSD 0.29 Å
- 8VFX chain E against the predicted model P68431: TM-score 0.99, RMSD 0.29 Å
- 8VG1 chain A against the predicted model P68431: TM-score 0.99, RMSD 0.29 Å
- 7K61 chain A against the predicted model P68431: TM-score 0.99, RMSD 0.29 Å
- 7K61 chain A against the predicted model P68431: TM-score 0.99, RMSD 0.29 Å
- 6JR1 chain A against the predicted model P68431: TM-score 0.99, RMSD 0.29 Å
- 8VFX chain A against the predicted model P68431: TM-score 0.99, RMSD 0.30 Å
- 3AFA chain A against the predicted model P68431: TM-score 0.99, RMSD 0.31 Å
- 7U0G chain A against the predicted model P68431: TM-score 0.99, RMSD 0.31 Å
Elsewhere
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