Research workbench
PT(II)-mediated copper-dependent interactions between ATOX1 and MNK1
Analyse PT(II)-mediated copper-dependent interactions between ATOX1 and MNK1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5T7L
- Type
- protein
- Length
- 143 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Copper transport protein ATOX1; Copper-transporting ATPase 1
- EC
- 3.6.3.54
- UniProt
- O00244, Q04656
- Ligands
- PT, CU
Structure
x-ray diffraction · 2 distinct chains · 31% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Copper transport protein ATOX1 | protein | 68 | 37% helix, 32% strand | O00244 |
| B | Copper-transporting ATPase 1 (EC 3.6.3.54) | protein | 75 | 27% helix, 39% strand | Q04656 |
Ligands and binding sites
- PT · Platinum (II) ion · metal · 2 copies · chains A, B
- CU · Copper (II) ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 519 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 5T7L · Pt(II)-mediated copper-dependent interactions between ATOX1 and MNK1 · the same entry in another collection · chain B against B, TM-score 1.00
- O00244 · AlphaFold monomer V2.0 prediction for copper transport protein ATOX1 (O00244) · a predicted model of the same protein · chain A against A, TM-score 0.96
- Q04656 · AlphaFold monomer V2.0 prediction for copper-transporting ATPase 1 (Q04656) · a predicted model of the same protein · chain B against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00244
- Every structure of UniProt Q04656
- Elsewhere: RCSB PDB 5T7L · PDBe 5T7L · UniProt O00244 · UniProt Q04656
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.