UniProt O00244
Copper transport protein ATOX1 (O00244)
Copper transport protein ATOX1 (UniProt O00244): 33 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00244
- Protein
- Copper transport protein ATOX1
- Experimental structures
- 33
- Predicted models
- 1
- Ligands
- 5
Structures
34 records of O00244 in the MolNFT archive: 33 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FE0 | Crystal structure of cadmium-HAH1 | x-ray diffraction | A, B | — | — |
| 1FE0 | Crystal structure of cadmium-HAH1 | x-ray diffraction | A, B | — | — |
| 1FE4 | Crystal structure of mercury-HAH1 | x-ray diffraction | A, B | — | — |
| 1FE4 | Crystal structure of mercury-HAH1 | x-ray diffraction | A, B | — | — |
| 1FEE | Crystal structure of copper-HAH1 | x-ray diffraction | A, B | — | — |
| 1FEE | Crystal structure of copper-HAH1 | x-ray diffraction | A, B | — | — |
| 1TL4 | Solution structure of Cu(I) HAH1 | solution nmr | A | — | — |
| 1TL4 | Solution structure of CU(I) HAH1 | solution nmr | A | — | — |
| 1TL5 | Solution structure of apoHAH1 | solution nmr | A | — | — |
| 1TL5 | Solution structure of APOHAH1 | solution nmr | A | — | — |
| 2K1R | The solution NMR structure of the complex between MNK1 and HAH1 mediated by Cu(I) | solution nmr | B | — | — |
| 2K1R | The solution NMR structure of the complex between MNK1 and HAH1 mediated by CU(I) | solution nmr | B | — | — |
| 2LQ9 | Solution structure of the K60A mutant of Atox1 | solution nmr | A | — | — |
| 2LQ9 | Solution structure of the K60A mutant of ATOX1 | solution nmr | A | — | — |
| 3CJK | Crystal structure of the adduct HAH1-Cd(II)-MNK1. | x-ray diffraction | A | — | — |
| 3CJK | Crystal structure of the adduct HAH1-CD(II)-MNK1. | x-ray diffraction | A | — | — |
| 3IWL | Crystal structure of cisplatin bound to a human copper chaperone (monomer) | x-ray diffraction | A | — | — |
| 3IWL | Crystal structure of cisplatin bound to a human copper chaperone (monomer) | x-ray diffraction | A | — | — |
| 3IWX | Crystal structure of cisplatin bound to a human copper chaperone (dimer) | x-ray diffraction | A, B | — | — |
| 3IWX | Crystal structure of cisplatin bound to a human copper chaperone (dimer) | x-ray diffraction | A, B | — | — |
| 4QOT | Crystal structure of human copper chaperone bound to the platinum ion | x-ray diffraction | A, B | — | — |
| 4QOT | Crystal structure of human copper chaperone bound to the platinum ion | x-ray diffraction | A, B | — | — |
| 4YDX | Crystal structure of cisplatin bound to a human copper chaperone (monomer) - new refinement | x-ray diffraction | A | — | — |
| 4YDX | Crystal structure of cisplatin bound to a human copper chaperone (monomer) - new refinement | x-ray diffraction | A | — | — |
| 4YEA | Crystal structure of cisplatin bound to a human copper chaperone (dimer) - new refinement | x-ray diffraction | A, B | — | — |
| 4YEA | Crystal structure of cisplatin bound to a human copper chaperone (dimer) - new refinement | x-ray diffraction | A, B | — | — |
| 5F0W | Crystal structure of human copper homeostatic proteins atox1 | x-ray diffraction | A, B, C, D | AG | — |
| 5F0W | Crystal structure of human copper homeostatic proteins ATOX1 | x-ray diffraction | A, B, C, D | — | — |
| 5T7L | Pt(II)-mediated copper-dependent interactions between ATOX1 and MNK1 | x-ray diffraction | A | PT, CU | — |
| 5T7L | PT(II)-mediated copper-dependent interactions between ATOX1 and MNK1 | x-ray diffraction | A | PT, CU | — |
| 7DC1 | Crystal structure of human copper homeostatic proteins atox1 | x-ray diffraction | A, B | AG | — |
| 7DC1 | Crystal structure of human copper homeostatic proteins ATOX1 | x-ray diffraction | A, B | AG | — |
| 7ZC3 | Crystal structure of human copper chaperone ATOX1 bound to zinc ion by cxxc motif | x-ray diffraction | A, B | ZN, SO4 | — |
| O00244 | AlphaFold monomer V2.0 prediction for copper transport protein ATOX1 (O00244) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4YDX chain A against the predicted model O00244: TM-score 0.99, RMSD 0.26 Å
- 4YDX chain A against the predicted model O00244: TM-score 0.99, RMSD 0.26 Å
- 3IWL chain A against the predicted model O00244: TM-score 0.99, RMSD 0.26 Å
- 3IWL chain A against the predicted model O00244: TM-score 0.99, RMSD 0.26 Å
- 1FEE chain B against the predicted model O00244: TM-score 0.99, RMSD 0.28 Å
- 1FEE chain B against the predicted model O00244: TM-score 0.99, RMSD 0.28 Å
- 1FE0 chain B against the predicted model O00244: TM-score 0.99, RMSD 0.30 Å
- 1FE0 chain B against the predicted model O00244: TM-score 0.99, RMSD 0.30 Å
- 3IWX chain A against the predicted model O00244: TM-score 0.99, RMSD 0.31 Å
- 3IWX chain A against the predicted model O00244: TM-score 0.99, RMSD 0.31 Å
Elsewhere
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