MolNFT v1 · #67859 · protein

Crystal structure of cisplatin bound to a human copper chaperone (dimer)

3IWX · Copper transport protein ATOX1: “Crystal structure of cisplatin bound to a human copper chaperone (dimer)”. X-ray diffraction, 2 ligands (CPT, SO4). MolNFT v1 #67859 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3IWX
Type: protein
Length: 134 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Copper transport protein ATOX1
UniProt: O00244
Ligands: CPT, SO4

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Copper transport protein ATOX1	protein	67	34% helix, 36% strand	O00244

Ligands and binding sites

CPT · Cisplatin · ligand · chains A, B
SO4 · Sulfate ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 482 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

3IWX · Crystal structure of cisplatin bound to a human copper chaperone (dimer) · the same entry in another collection · chain A against A, TM-score 1.00
O00244 · AlphaFold monomer V2.0 prediction for copper transport protein ATOX1 (O00244) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O00244
Elsewhere: RCSB PDB 3IWX · PDBe 3IWX · UniProt O00244

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.