UniProt Q04656
Copper-transporting ATPase 1 (Q04656)
Copper-transporting ATPase 1 (UniProt Q04656), EC 3.6.3.54: 43 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q04656
- Protein
- Copper-transporting ATPase 1
- EC
- 3.6.3.54
- Experimental structures
- 43
- Predicted models
- 1
- Ligands
- 2
Structures
44 records of Q04656 in the MolNFT archive: 43 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AW0 | Fourth metal-binding domain of the menkes copper-transporting ATPase, NMR, 20 structures | solution nmr | A | — | — |
| 1AW0 | Fourth metal-binding domain of the menkes copper-transporting ATPase, NMR, 20 structures | solution nmr | A | — | — |
| 1KVI | Solution Structure of the Reduced Form of the First Heavy Metal Binding Motif of the Menkes Protein | solution nmr | A | — | — |
| 1KVI | Solution structure of the reduced form of the first heavy metal binding motif of the menkes protein | solution nmr | A | — | — |
| 1KVJ | Solution Structure of the Cu(I) bound form of the first heavy metal binding motif of the Menkes… | solution nmr | A | — | — |
| 1KVJ | Solution structure of the CU(I) bound form of the first heavy metal binding motif of the menkes… | solution nmr | A | — | — |
| 1Q8L | Second Metal Binding Domain of the Menkes ATPase | solution nmr | A | — | — |
| 1Q8L | Second metal binding domain of the menkes ATPase | solution nmr | A | — | — |
| 1S6O | Solution structure and backbone dynamics of the apo-form of the second metal-binding domain of the… | solution nmr | A | — | — |
| 1S6O | Solution structure and backbone dynamics of the apo-form of the second metal-binding domain of the… | solution nmr | A | — | — |
| 1S6U | Solution structure and backbone dynamics of the Cu(I) form of the second metal-binding domain of… | solution nmr | A | — | — |
| 1S6U | Solution structure and backbone dynamics of the CU(I) form of the second metal-binding domain of… | solution nmr | A | — | — |
| 1Y3J | Solution structure of the copper(I) form of the fifth domain of Menkes protein | solution nmr | A | — | — |
| 1Y3J | Solution structure of the COPPER(I) form of the fifth domain of menkes protein | solution nmr | A | — | — |
| 1Y3K | Solution structure of the apo form of the fifth domain of Menkes protein | solution nmr | A | — | — |
| 1Y3K | Solution structure of the apo form of the fifth domain of menkes protein | solution nmr | A | — | — |
| 1YJR | Solution structure of the apo form of the sixth soluble domain A69P mutant of Menkes protein | solution nmr | A | — | — |
| 1YJR | Solution structure of the apo form of the sixth soluble domain A69P mutant of menkes protein | solution nmr | A | — | — |
| 1YJT | Solution structure of the Cu(I) form of the sixth soluble domain A69P mutant of Menkes protein | solution nmr | A | — | — |
| 1YJT | Solution structure of the CU(I) form of the sixth soluble domain A69P mutant of menkes protein | solution nmr | A | — | — |
| 1YJU | Solution structure of the apo form of the sixth soluble domain of Menkes protein | solution nmr | A | — | — |
| 1YJU | Solution structure of the apo form of the sixth soluble domain of menkes protein | solution nmr | A | — | — |
| 1YJV | Solution structure of the Cu(I) form of the sixth soluble domain of Menkes protein | solution nmr | A | — | — |
| 1YJV | Solution structure of the CU(I) form of the sixth soluble domain of menkes protein | solution nmr | A | — | — |
| 2AW0 | Fourth metal-binding domain of the menkes copper-transporting ATPase, NMR, 20 structures | solution nmr | A | — | — |
| 2AW0 | Fourth metal-binding domain of the menkes copper-transporting ATPase, NMR, 20 structures | solution nmr | A | — | — |
| 2G9O | Solution structure of the apo form of the third metal-binding domain of ATP7A protein (Menkes… | solution nmr | A | — | — |
| 2G9O | Solution structure of the apo form of the third metal-binding domain of ATP7A protein (menkes… | solution nmr | A | — | — |
| 2GA7 | Solution structure of the copper(I) form of the third metal-binding domain of ATP7A protein (menkes… | solution nmr | A | — | — |
| 2GA7 | Solution structure of the COPPER(I) form of the third metal-binding domain of ATP7A protein (menkes… | solution nmr | A | — | — |
| 2K1R | The solution NMR structure of the complex between MNK1 and HAH1 mediated by Cu(I) | solution nmr | A | — | — |
| 2K1R | The solution NMR structure of the complex between MNK1 and HAH1 mediated by CU(I) | solution nmr | A | — | — |
| 2KIJ | Solution structure of the Actuator domain of the copper-transporting ATPase ATP7A | solution nmr | A | — | — |
| 2KIJ | Solution structure of the actuator domain of the copper-transporting ATPase ATP7A | solution nmr | A | — | — |
| 2KMV | Solution structure of the nucleotide binding domain of the human Menkes protein in the ATP-free form | solution nmr | A | — | — |
| 2KMV | Solution structure of the nucleotide binding domain of the human menkes protein in the ATP-free form | solution nmr | A | — | — |
| 2KMX | Solution structure of the nucleotide binding domain of the human Menkes protein in the ATP-bound… | solution nmr | A | — | — |
| 2KMX | Solution structure of the nucleotide binding domain of the human menkes protein in the ATP-bound… | solution nmr | A | — | — |
| 3CJK | Crystal structure of the adduct HAH1-Cd(II)-MNK1. | x-ray diffraction | B | — | — |
| 3CJK | Crystal structure of the adduct HAH1-CD(II)-MNK1. | x-ray diffraction | B | — | — |
| 5T7L | Pt(II)-mediated copper-dependent interactions between ATOX1 and MNK1 | x-ray diffraction | B | PT, CU | — |
| 5T7L | PT(II)-mediated copper-dependent interactions between ATOX1 and MNK1 | x-ray diffraction | B | PT, CU | — |
| 7LU8 | Structure of the cryptic hma domain of the human copper transporter ATP7A | solution nmr | A | — | — |
| Q04656 | AlphaFold monomer V2.0 prediction for copper-transporting ATPase 1 (Q04656) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1AW0 chain A against the predicted model Q04656: TM-score 0.96, RMSD 0.63 Å
- 1AW0 chain A against the predicted model Q04656: TM-score 0.96, RMSD 0.63 Å
- 2AW0 chain A against the predicted model Q04656: TM-score 0.95, RMSD 0.67 Å
- 2AW0 chain A against the predicted model Q04656: TM-score 0.95, RMSD 0.67 Å
- 1YJV chain A against the predicted model Q04656: TM-score 0.91, RMSD 1.17 Å
- 1YJV chain A against the predicted model Q04656: TM-score 0.91, RMSD 1.17 Å
- 1YJR chain A against the predicted model Q04656: TM-score 0.90, RMSD 1.31 Å
- 1YJR chain A against the predicted model Q04656: TM-score 0.90, RMSD 1.31 Å
- 1YJU chain A against the predicted model Q04656: TM-score 0.90, RMSD 1.64 Å
- 1YJU chain A against the predicted model Q04656: TM-score 0.90, RMSD 1.64 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.