Research workbench
Udp-glucose glycoprotein glucosyltransferase from chaetomium thermophilum soaked with K2PTI6
Analyse Udp-glucose glycoprotein glucosyltransferase from chaetomium thermophilum… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5MU1
- Type
- protein
- Length
- 1,377 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Udp-glucose-glycoprotein glucosyltransferase-like protein
- UniProt
- G0SB58
- Ligands
- MAN, NAG, BMA, PT, CA, IOD
- Pockets
- 18 · best druggability 0.82
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Udp-glucose-glycoprotein glucosyltransferase-like protein | protein | 1377 | 38% helix, 18% strand | G0SB58 |
Ligands and binding sites
- MAN · alpha-D-mannopyranose · sugar · 12 copies
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 8 copies · chains A
- BMA · beta-D-mannopyranose · sugar · 4 copies
- PT · Platinum (II) ion · metal · 6 copies · chains A
- CA · Calcium ion · metal · chains A
- IOD · Iodide ion · ion · 14 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
18 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1097 | 0.82 | 0.83 | 101 | CA |
| 2 | 663 | 0.82 | 0.86 | 74 | empty |
| 3 | 304 | 0.71 | 0.85 | 33 | empty |
| 4 | 174 | 0.69 | 0.87 | 27 | empty |
| 5 | 160 | 0.60 | 0.83 | 26 | empty |
Modifications
Observed in the structure: 4 glycan, 3 disulfide (N-glycosylation, disulfide).
Compared structures
- 5MU1 · UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum soaked with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0SB58
- Elsewhere: RCSB PDB 5MU1 · PDBe 5MU1 · UniProt G0SB58
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