Research workbench
Crystal structure of phosphatidyl inositol 4-kinase II alpha in the apo state
Analyse Crystal structure of phosphatidyl inositol 4-kinase II alpha in the apo state in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5EUT
- Type
- protein
- Length
- 485 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphatidylinositol 4-kinase type 2-ALPHA,ENDOLYSIN, phosphatidylinositol 4-kinase type…
- EC
- 2.7.1.67, 3.2.1.17
- UniProt
- Q9BTU6, P00720
- Pockets
- 5 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 51% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 4-kinase type 2-ALPHA,ENDOLYSIN, phosphatidylinositol 4-kinase type 2-alpha (EC 2.7.1.67, 3.2.1.17) | protein | 485 | 51% helix, 11% strand | Q9BTU6, P00720 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 596 | 0.70 | 0.79 | 66 | empty |
| 2 | 283 | 0.54 | 0.76 | 30 | empty |
| 3 | 102 | 0.51 | 0.82 | 16 | empty |
| 4 | 119 | 0.40 | 0.75 | 23 | empty |
| 5 | 80 | 0.38 | 0.78 | 23 | empty |
Compared structures
- 5EUT · Crystal structure of phosphatidyl inositol 4-kinase II alpha in the apo state · the same entry in another collection · chain A against A, TM-score 1.00
- Q9BTU6 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-kinase type 2-alpha (Q9BTU6) · a predicted model of the same protein · chain A against A, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BTU6
- Every structure of UniProt P00720
- Elsewhere: RCSB PDB 5EUT · PDBe 5EUT · UniProt Q9BTU6 · UniProt P00720
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