MolNFT v1 · #284690 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-kinase type 2-alpha (Q9BTU6)
Q9BTU6: “AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-kinase type 2-alpha (Q9BTU6)”. 7 pockets (best druggability 0.71). MolNFT v1 #284690 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9BTU6
- Type
- protein
- Length
- 479 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xaa53776A41fB2e67da75A96E8a53746b6874aAB4
- Molecule
- Phosphatidylinositol 4-kinase type 2-alpha
- UniProt
- Q9BTU6
- Pockets
- 7 · best druggability 0.71
Structure
1 distinct chain · 40% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 4-kinase type 2-alpha | protein | 479 | 40% helix, 11% strand | Q9BTU6 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 296 | 0.71 | 0.85 | 53 | empty |
| 2 | 164 | 0.55 | 0.80 | 25 | empty |
| 3 | 223 | 0.52 | 0.76 | 29 | empty |
| 4 | 247 | 0.50 | 0.74 | 35 | empty |
| 5 | 132 | 0.39 | 0.74 | 21 | empty |
Compared structures
- 4HNE · Crystal structure of the catalytic domain of human type II alpha Phosphatidylinositol… · an experimental structure of the same protein · chain A against A, TM-score 0.66
- 4HNE · Crystal structure of the catalytic domain of human type II alpha phosphatidylinositol… · an experimental structure of the same protein · chain A against A, TM-score 0.66
- 4HND · Crystal structure of the catalytic domain of Selenomethionine substituted human… · an experimental structure of the same protein · chain A against A, TM-score 0.66
- 4HND · Crystal structure of the catalytic domain of selenomethionine substituted human… · an experimental structure of the same protein · chain A against A, TM-score 0.66
- 5I0N · PI4K iialpha bound to calcium · an experimental structure of the same protein · chain A against A, TM-score 0.66
- 5I0N · PI4K IIalpha bound to calcium · an experimental structure of the same protein · chain A against A, TM-score 0.66
- 4YC4 · Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with nucleotide… · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 4YC4 · Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with nucleotide… · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 5EUT · Crystal structure of phosphatidyl inositol 4-kinase II alpha in the apo state · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 5EUT · Crystal structure of phosphatidyl inositol 4-kinase II alpha in the apo state · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 4PLA · Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with ATP · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 4PLA · Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with ATP · an experimental structure of the same protein · chain A against A, TM-score 0.65
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BTU6
- Elsewhere: UniProt Q9BTU6 · AlphaFold DB Q9BTU6
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