UniProt Q9BTU6
Phosphatidylinositol 4-kinase type 2-alpha (Q9BTU6)
Phosphatidylinositol 4-kinase type 2-alpha (UniProt Q9BTU6): 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9BTU6
- Protein
- Phosphatidylinositol 4-kinase type 2-alpha
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 1 record with a druggable one
Structures
13 records of Q9BTU6 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4HND | Crystal structure of the catalytic domain of Selenomethionine substituted human PI4KIIalpha in… | x-ray diffraction | A, B | — | — |
| 4HND | Crystal structure of the catalytic domain of selenomethionine substituted human PI4KIIALPHA in… | x-ray diffraction | A, B | — | — |
| 4HNE | Crystal structure of the catalytic domain of human type II alpha Phosphatidylinositol 4-kinase… | x-ray diffraction | A, B | — | — |
| 4HNE | Crystal structure of the catalytic domain of human type II alpha phosphatidylinositol 4-kinase… | x-ray diffraction | A, B | — | — |
| 4PLA | Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with ATP | x-ray diffraction | A | — | — |
| 4PLA | Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with ATP | x-ray diffraction | A | — | — |
| 4YC4 | Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with nucleotide analog | x-ray diffraction | A | — | — |
| 4YC4 | Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with nucleotide analog | x-ray diffraction | A | — | — |
| 5EUT | Crystal structure of phosphatidyl inositol 4-kinase II alpha in the apo state | x-ray diffraction | A | — | — |
| 5EUT | Crystal structure of phosphatidyl inositol 4-kinase II alpha in the apo state | x-ray diffraction | A | — | — |
| 5I0N | PI4K IIalpha bound to calcium | x-ray diffraction | A | ATP, CA | — |
| 5I0N | PI4K iialpha bound to calcium | x-ray diffraction | A | — | — |
| Q9BTU6 | AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-kinase type 2-alpha (Q9BTU6) | predicted | A | — | 7 (best 0.71) |
Ligands
Experiment against prediction
- 4HNE chain A against the predicted model Q9BTU6: TM-score 0.90, RMSD 1.75 Å
- 4HNE chain A against the predicted model Q9BTU6: TM-score 0.90, RMSD 1.75 Å
- 4HND chain A against the predicted model Q9BTU6: TM-score 0.90, RMSD 1.77 Å
- 4HND chain A against the predicted model Q9BTU6: TM-score 0.90, RMSD 1.77 Å
- 4HND chain B against the predicted model Q9BTU6: TM-score 0.88, RMSD 1.85 Å
- 4HND chain B against the predicted model Q9BTU6: TM-score 0.88, RMSD 1.85 Å
- 4HNE chain B against the predicted model Q9BTU6: TM-score 0.88, RMSD 2.05 Å
- 4HNE chain B against the predicted model Q9BTU6: TM-score 0.88, RMSD 2.05 Å
- 5I0N chain A against the predicted model Q9BTU6: TM-score 0.64, RMSD 2.03 Å
- 5I0N chain A against the predicted model Q9BTU6: TM-score 0.64, RMSD 2.03 Å
Elsewhere
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