UniProt P00720
Endolysin (P00720)
Endolysin (UniProt P00720), EC 2.3.2.27, 3.2.1.17: 1,371 experimental structures on GenesisL1, 70 ligands bound, 196 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P00720
- Protein
- Endolysin
- EC
- 2.3.2.27, 3.2.1.17
- Experimental structures
- 1,371
- Predicted models
- 0
- Ligands
- 70
- Pockets
- 196 · 41 records with a druggable one
Structures
1,371 records of P00720 in the MolNFT archive: 1371 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 102L | How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme | x-ray diffraction | A | — | — |
| 102L | How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme | x-ray diffraction | A | — | — |
| 102L | How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme | x-ray diffraction | A | — | — |
| 103L | How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme | x-ray diffraction | A | — | — |
| 103L | How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme | x-ray diffraction | A | — | — |
| 103L | How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme | x-ray diffraction | A | — | — |
| 104L | How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme | x-ray diffraction | A, B | — | — |
| 104L | How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme | x-ray diffraction | A, B | — | — |
| 104L | 104l | x-ray diffraction | A, B | — | — |
| 107L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 107L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 108L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 108L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 109L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 109L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 110L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 110L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 111L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 111L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 112L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 112L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 113L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 113L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 114L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 114L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 115L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 115L | Structural basis of alpha-helix propensity at two sites in T4 lysozyme | x-ray diffraction | A | — | — |
| 118L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 118L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 119L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 119L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 120L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 120L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 122L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 122L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 123L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 123L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 125L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 125L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 126L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 126L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 127L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 127L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 128L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 128L | The energetic cost and the structural consequences of burying a hydroxyl group within the core of a… | x-ray diffraction | A | — | — |
| 129L | Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced… | x-ray diffraction | A | — | — |
| 129L | Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced… | x-ray diffraction | A | — | — |
| 130L | Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced… | x-ray diffraction | A | — | — |
| 130L | Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced… | x-ray diffraction | A | — | — |
| 131L | Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced… | x-ray diffraction | A | — | — |
| 131L | Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced… | x-ray diffraction | A | — | — |
| 137L | Structural basis of amino acid alpha helix propensity | x-ray diffraction | A, B | — | — |
| 137L | Structural basis of amino acid alpha helix propensity | x-ray diffraction | A, B | — | — |
| 138L | Rapid crystallization of T4 lysozyme by intermolecular disulfide crosslinking | x-ray diffraction | A | — | — |
| 138L | Rapid crystallization of T4 lysozyme by intermolecular disulfide crosslinking | x-ray diffraction | A | — | — |
| 139L | Rapid crystallization of T4 lysozyme by intermolecular disulfide crosslinking | x-ray diffraction | A | — | — |
| 139L | Rapid crystallization of T4 lysozyme by intermolecular disulfide crosslinking | x-ray diffraction | A | — | — |
| 140L | Role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme | x-ray diffraction | A | — | — |
| 140L | Role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme | x-ray diffraction | A | — | — |
| 141L | Role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme | x-ray diffraction | A | — | — |
1,311 records more on the page itself.
Ligands
- CL · Chloride ion · in 39 records
- PO4 · Phosphate ion · in 15 records
- OLA · Oleic acid · in 13 records
- K · Potassium ion · in 11 records
- SO4 · Sulfate ion · in 10 records
- V1A · S-(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-imidazol-4-yl) methanesulfonothioate · in 8 records
- 97Y · N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine · in 6 records
- NA · Sodium ion · in 6 records
- CA · Calcium ion · in 5 records
- ZN · Zinc ion · in 5 records
- CLR · Cholesterol · in 4 records
- UKA · 6-(2,2-diphenylethylamino)-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]-N-[2-[(1-pyridin-2-ylpiperidin-4-yl) carbamoylamino]ethyl]purine-2-carboxamide · in 4 records
- CAU · (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol · in 3 records
- J0Z · benzyl acetate · in 3 records
- MBN · Toluene · in 3 records
- MK6 · (5ar,6s,6as)-3-({2',6'-dimethyl-4'-[3-(methylsulfonyl) propoxy][1,1'-biphenyl]-3-yl}methoxy)-5,5A,6,6A-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid · in 3 records
- XQM · 1-iodo-4-methylbenzene · in 3 records
- 0HK · (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane · in 2 records
- 6OQ · 2-ethyl-1,2-dihydro-1,2-azaborinine · in 2 records
- 97V · 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl) phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl) benzamide · in 2 records
- 9EU · 4-ethynyl-3-{3-fluoro-4-[(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]benzene-1-carbonyl}-N,N-dimethyl-1H-indole-1-carboxamide · in 2 records
- ACM · Acetamide · in 2 records
- ATP · Adenosine-5'-triphosphate · in 2 records
- BGC · beta-D-glucopyranose · in 2 records
- D2U · (2~{S})-2-[[(2~{R})-2-[(3,5-dimethylphenyl)carbonyl-methyl-amino]-3-(4-phenylphenyl)propanoyl]amino]-3-(1~{H}-indol-3-yl)propanoic acid · in 2 records
- DQD · N-[(2H-1,3-benzodioxol-5-yl)methyl]-N-(1-propylpiperidin-4-yl)-N'-[3-(trifluoromethyl) phenyl]urea · in 2 records
- GLC · alpha-D-glucopyranose · in 2 records
- K86 · 4-tert-butyl-N-[6-(2-hydroxyethyloxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-pyrimidin-4-yl]benzenesulfonamide · in 2 records
- MG · Magnesium ion · in 2 records
- MTN · S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate · in 2 records
Experiment against prediction
- 8THK chain R against the predicted model P35348: TM-score 0.97, RMSD 1.30 Å
- 8THL chain R against the predicted model P35348: TM-score 0.96, RMSD 1.30 Å
- 5ZKQ chain A against the predicted model P25105: TM-score 0.96, RMSD 1.55 Å
- 5ZKQ chain A against the predicted model P25105: TM-score 0.96, RMSD 1.55 Å
- 4HTT chain A against the predicted model O67305: TM-score 0.95, RMSD 1.40 Å
- 4HTT chain A against the predicted model O67305: TM-score 0.95, RMSD 1.40 Å
- 3P0G chain A against the predicted model P07550: TM-score 0.94, RMSD 1.94 Å
- 3P0G chain A against the predicted model P07550: TM-score 0.94, RMSD 1.94 Å
- 9CBM chain R against the predicted model P08913: TM-score 0.93, RMSD 1.96 Å
- 5TZR chain A against the predicted model O14842: TM-score 0.62, RMSD 0.97 Å
Elsewhere
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