Research workbench
hTRiC-hPFD Class1 (No PFD)
Analyse hTRiC-hPFD Class1 (No PFD) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6NRA
- Type
- protein
- Length
- 8,221 residues
- Chains
- 16
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 7.7
- Source
- Homo sapiens
- Molecule
- T-complex protein 1 subunit alpha; T-complex protein 1 subunit beta; T-complex protein 1…
- UniProt
- P17987, P78371, P49368, P50991, P48643, P40227, Q99832, P50990
- Pockets
- 20 · best druggability 0.83
Structure
electron microscopy · resolution 7.7 · 15 distinct chains · 49% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | T-complex protein 1 subunit alpha | protein | 521 | 46% helix, 12% strand | P17987 |
| B | T-complex protein 1 subunit beta | protein | 509 | 50% helix, 17% strand | P78371 |
| C | T-complex protein 1 subunit gamma | protein | 509 | 51% helix, 13% strand | P49368 |
| D | T-complex protein 1 subunit delta | protein | 508 | 50% helix, 14% strand | P50991 |
| E, M | T-complex protein 1 subunit epsilon | protein | 517 | 48% helix, 9% strand | P48643 |
| F | T-complex protein 1 subunit zeta | protein | 514 | 51% helix, 17% strand | P40227 |
| G | T-complex protein 1 subunit eta | protein | 512 | 47% helix, 13% strand | Q99832 |
| H | T-complex protein 1 subunit theta | protein | 510 | 47% helix, 12% strand | P50990 |
| I | T-complex protein 1 subunit alpha | protein | 534 | 45% helix, 12% strand | P17987 |
| J | T-complex protein 1 subunit beta | protein | 508 | 50% helix, 16% strand | P78371 |
| K | T-complex protein 1 subunit gamma | protein | 513 | 49% helix, 11% strand | P49368 |
| L | T-complex protein 1 subunit delta | protein | 513 | 48% helix, 11% strand | P50991 |
| N | T-complex protein 1 subunit zeta | protein | 513 | 51% helix, 15% strand | P40227 |
| O | T-complex protein 1 subunit eta | protein | 514 | 49% helix, 14% strand | Q99832 |
| P | T-complex protein 1 subunit theta | protein | 509 | 49% helix, 13% strand | P50990 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 291 | 0.83 | 0.93 | 48 | empty |
| 2 | 449 | 0.82 | 0.90 | 49 | empty |
| 3 | 920 | 0.82 | 0.83 | 84 | empty |
| 4 | 182 | 0.81 | 0.96 | 28 | empty |
| 5 | 183 | 0.81 | 0.97 | 39 | empty |
Interfaces
33 interfaces between chains.
- M–O · 3857 Ų buried · 39 hydrogen bonds · protein-protein
- E–G · 3798 Ų buried · 45 hydrogen bonds · protein-protein
- I–K · 2377 Ų buried · 27 hydrogen bonds · protein-protein
- J–L · 2215 Ų buried · 15 hydrogen bonds · protein-protein
- I–L · 2144 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
- 6NRA · Htric-hpfd CLASS1 (no pfd) · the same entry in another collection · chain J against J, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17987
- Every structure of UniProt P78371
- Every structure of UniProt P49368
- Every structure of UniProt P50991
- Every structure of UniProt P48643
- Every structure of UniProt P40227
- Every structure of UniProt Q99832
- Every structure of UniProt P50990
- Elsewhere: RCSB PDB 6NRA · PDBe 6NRA · UniProt P17987 · UniProt P78371 · UniProt P49368 · UniProt P50991 · UniProt P48643 · UniProt P40227 · UniProt Q99832 · UniProt P50990
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