UniProt Q99832
T-complex protein 1 subunit eta (Q99832)
T-complex protein 1 subunit eta (UniProt Q99832): 59 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 225 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99832
- Protein
- T-complex protein 1 subunit eta
- Experimental structures
- 59
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 225 · 44 records with a druggable one
Structures
60 records of Q99832 in the MolNFT archive: 59 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NR8 | hTRiC-hPFD Class6 | electron microscopy | G, O | — | 6 (best 0.83) |
| 6NR8 | Htric-hpfd CLASS6 | electron microscopy | G, O | — | — |
| 6NR9 | hTRiC-hPFD Class5 | electron microscopy | G, O | — | 2 (best 0.84) |
| 6NR9 | Htric-hpfd CLASS5 | electron microscopy | G, O | — | — |
| 6NRA | hTRiC-hPFD Class1 (No PFD) | electron microscopy | G, O | — | — |
| 6NRA | Htric-hpfd CLASS1 (no pfd) | electron microscopy | G, O | — | — |
| 6NRB | hTRiC-hPFD Class2 | electron microscopy | G, O | — | 4 (best 0.84) |
| 6NRB | Htric-hpfd CLASS2 | electron microscopy | G, O | — | — |
| 6NRC | hTRiC-hPFD Class3 | electron microscopy | G, O | — | 3 (best 0.84) |
| 6NRC | Htric-hpfd CLASS3 | electron microscopy | G, O | — | — |
| 6NRD | hTRiC-hPFD Class4 | electron microscopy | G, O | — | 4 (best 0.84) |
| 6NRD | Htric-hpfd CLASS4 | electron microscopy | G, O | — | — |
| 6QB8 | Human CCT:mLST8 complex | electron microscopy | h, H | — | 6 (best 0.84) |
| 6QB8 | Human CCT:MLST8 complex | electron microscopy | h, H | — | — |
| 7LUM | Human TRiC in ATP/AlFx closed state | electron microscopy | K, C | — | 7 (best 0.85) |
| 7LUM | Human tric in ATP/ALFX closed state | electron microscopy | K, C | — | — |
| 7LUP | Human TRiC/CCT complex with reovirus outer capsid protein sigma-3 | electron microscopy | K, C | — | 6 (best 0.85) |
| 7LUP | Human TRIC/CCT complex with reovirus outer capsid protein sigma-3 | electron microscopy | K, C | — | — |
| 7NVL | Human TRiC complex in closed state with nanobody bound (Consensus Map) | electron microscopy | H, h | ADP, MG, AF3 | — |
| 7NVL | Human tric complex in closed state with nanobody bound (consensus MAP) | electron microscopy | H, h | ADP, MG, AF3 | — |
| 7NVM | Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound | electron microscopy | H, h | ADP, MG, AF3 | — |
| 7NVM | Human tric complex in closed state with nanobody NB18, actin and PHLP2A bound | electron microscopy | H, h | ADP, MG, AF3 | — |
| 7NVN | Human TRiC complex in closed state with nanobody and tubulin bound | electron microscopy | H, h | ADP, MG, AF3 | 5 (best 0.85) |
| 7NVN | Human tric complex in closed state with nanobody and tubulin bound | electron microscopy | H, h | ADP, MG, AF3 | — |
| 7NVO | Human tric complex in open state with nanobody bound | electron microscopy | H, h | ADP, MG, AF3 | — |
| 7TTN | The beta-tubulin folding intermediate II | electron microscopy | C | MG, ADP, AF3 | 4 (best 0.78) |
| 7TTT | The beta-tubulin folding intermediate III | electron microscopy | C | MG, ADP, AF3 | 4 (best 0.86) |
| 7TUB | The beta-tubulin folding intermediate IV | electron microscopy | C | MG, ADP, AF3 | 2 (best 0.77) |
| 7WU7 | Prefoldin-tubulin-TRiC complex | electron microscopy | G, O | — | 6 (best 0.81) |
| 7WZ3 | Cryo-EM structure of human TRiC-tubulin-S1 state | electron microscopy | h, H | — | 4 (best 0.84) |
| 7X0A | Cryo-EM structure of human TRiC-NPP state | electron microscopy | h, H | — | 4 (best 0.85) |
| 7X0S | Human TRiC-tubulin-S3 | electron microscopy | H, O | ADP, MG, AF3 | 8 (best 0.84) |
| 7X0V | cryo-EM structure of human TRiC-ADP-AlFx | electron microscopy | H, O | ADP, MG, AF3 | 6 (best 0.86) |
| 7X3J | Cryo-EM structure of human TRiC-tubulin-S2 | electron microscopy | H, h | ATP | 5 (best 0.85) |
| 7X3U | cryo-EM structure of human TRiC-ADP | electron microscopy | h, H | ADP | 4 (best 0.85) |
| 7X7Y | Cryo-EM structure of Human TRiC-ATP-open state | electron microscopy | H, h | — | 5 (best 0.85) |
| 8HKI | Human TRiC open state | electron microscopy | h, H | — | 4 (best 0.84) |
| 8I1U | Human TRiC-PhLP2A complex in the closed state | electron microscopy | G, O | ADP, MG, AF3 | 6 (best 0.88) |
| 8I9U | Human TRiC-PhLP2A complex in the open state | electron microscopy | G, O | — | 6 (best 0.84) |
| 8IB8 | Human TRiC-PhLP2A-actin complex in the closed state | electron microscopy | G, O | — | 4 (best 0.88) |
| 8SFE | Open state CCT-G beta 5 complex | electron microscopy | h, H | ADP | 7 (best 0.84) |
| 8SFF | CCT G beta 5 complex closed state 0 | electron microscopy | H, h | ADP, MG, AF3 | 4 (best 0.86) |
| 8SG8 | CCT G beta 5 complex closed state 1 | electron microscopy | H, h | ADP, MG, AF3 | 4 (best 0.85) |
| 8SG9 | CCT G beta 5 complex closed state 3 | electron microscopy | H, h | ADP, MG, AF3 | 5 (best 0.86) |
| 8SGC | CCT G beta 5 complex closed state 2 | electron microscopy | H, h | ADP, MG, AF3 | 5 (best 0.86) |
| 8SGL | CCT G beta 5 complex closed state 15 | electron microscopy | H, h | ADP, MG, AF3 | 5 (best 0.85) |
| 8SGQ | CCT G beta 5 complex intermediate state | electron microscopy | h, H | ADP | 4 (best 0.86) |
| 8SH9 | CCT G beta 5 complex best PhLP1 class | electron microscopy | H, h | ADP, MG, AF3 | 7 (best 0.86) |
| 8SHA | CCT-G beta 5 complex closed state 4 | electron microscopy | H, h | ADP, MG, AF3 | 7 (best 0.86) |
| 8SHD | CCT G beta 5 complex closed state 10 | electron microscopy | H, h | ADP, MG, AF3 | 5 (best 0.89) |
| 8SHE | CCT-G beta 5 complex closed state 8 | electron microscopy | H, h | ADP, MG, AF3 | 5 (best 0.88) |
| 8SHF | CCT-G beta 5 complex closed state 7 | electron microscopy | H, h | ADP, MG, AF3 | 6 (best 0.87) |
| 8SHG | CCT G beta 5 complex closed state 9 | electron microscopy | H, h | ADP, MG, AF3 | 6 (best 0.87) |
| 8SHL | CCT G beta 5 complex closed state 5 | electron microscopy | H, h | ADP, MG, AF3 | 6 (best 0.84) |
| 8SHN | CCT-G beta 5 complex closed state 6 | electron microscopy | H, h | ADP, MG, AF3 | 7 (best 0.90) |
| 8SHO | CCT G beta 5 complex close state 11 | electron microscopy | H, h | ADP, MG, AF3 | 5 (best 0.86) |
| 8SHP | CCT G beta 5 complex closed state 13 | electron microscopy | H, h | ADP, MG, AF3 | 7 (best 0.88) |
| 8SHQ | CCT G beta 5 complex closed state 12 | electron microscopy | H, h | ADP, MG, AF3 | 7 (best 0.88) |
| 8SHT | CCT G beta 5 complex closed state 14 | electron microscopy | H, h | ADP, MG, AF3 | 6 (best 0.86) |
| Q99832 | AlphaFold monomer V2.0 prediction for T-complex protein 1 subunit eta (Q99832) | predicted | A | — | 2 (best 0.74) |
Ligands
Experiment against prediction
- 7NVL chain H against the predicted model Q99832: TM-score 0.98, RMSD 1.36 Å
- 7NVL chain H against the predicted model Q99832: TM-score 0.98, RMSD 1.36 Å
- 8I1U chain O against the predicted model Q99832: TM-score 0.97, RMSD 1.47 Å
- 8I1U chain G against the predicted model Q99832: TM-score 0.97, RMSD 1.50 Å
- 7NVM chain h against the predicted model Q99832: TM-score 0.97, RMSD 1.59 Å
- 7NVM chain h against the predicted model Q99832: TM-score 0.97, RMSD 1.59 Å
- 7NVN chain H against the predicted model Q99832: TM-score 0.97, RMSD 1.60 Å
- 7NVN chain H against the predicted model Q99832: TM-score 0.97, RMSD 1.60 Å
- 8HKI chain H against the predicted model Q99832: TM-score 0.97, RMSD 1.26 Å
- 8SHO chain h against the predicted model Q99832: TM-score 0.97, RMSD 1.63 Å
Elsewhere
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