MolNFT v1 · #183587 · protein
Human tric complex in closed state with nanobody NB18, actin and PHLP2A bound
7NVM: “Human tric complex in closed state with nanobody NB18, actin and PHLP2A bound”. Electron microscopy, 3 ligands (ADP, AF3, MG). MolNFT v1 #183587 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7NVM
- Type
- protein
- Length
- 9,219 residues
- Chains
- 20
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P17987, P78371, P50991, P48643, P49368, Q99832, P50990, P40227, P63261, Q9H2J4
- Ligands
- ADP, AF3, MG
Structure
electron microscopy · 18 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 536 | — | P17987 |
| B | — | protein | 526 | — | P78371 |
| D, d | — | protein | 520 | — | P50991 |
| E | — | protein | 535 | — | P48643 |
| G | — | protein | 526 | — | P49368 |
| H | — | protein | 528 | — | Q99832 |
| N, n | — | protein | 119 | — | — |
| Q | — | protein | 538 | — | P50990 |
| Z | — | protein | 525 | — | P40227 |
| a | — | protein | 532 | — | P17987 |
| b | — | protein | 525 | — | P78371 |
| e | — | protein | 540 | — | P48643 |
| g | — | protein | 538 | — | P49368 |
| h | — | protein | 525 | — | Q99832 |
| q | — | protein | 533 | — | P50990 |
| z | — | protein | 527 | — | P40227 |
| K | — | protein | 317 | — | P63261 |
| P | — | protein | 190 | — | Q9H2J4 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · 16 copies · chains A, B, D, E, G, H, Q, Z, a, b, d, e, g, h, q, z
- AF3 · Aluminum fluoride · ligand · 16 copies · chains A, B, D, E, G, H, Q, Z, a, b, d, e, g, h, q, z
- MG · Magnesium ion · metal · 16 copies · chains A, B, D, E, G, H, Q, Z, a, b, d, e, g, h, q, z
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7NVM · Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound · the same entry in another collection · chain b against b, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17987
- Every structure of UniProt P78371
- Every structure of UniProt P50991
- Every structure of UniProt P48643
- Every structure of UniProt P49368
- Every structure of UniProt Q99832
- Every structure of UniProt P50990
- Every structure of UniProt P40227
- Every structure of UniProt P63261
- Every structure of UniProt Q9H2J4
- Elsewhere: RCSB PDB 7NVM · PDBe 7NVM · UniProt P17987 · UniProt P78371 · UniProt P50991 · UniProt P48643 · UniProt P49368 · UniProt Q99832 · UniProt P50990 · UniProt P40227 · UniProt P63261 · UniProt Q9H2J4
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