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AlphaFold monomer V2.0 prediction for small glutamine-rich tetratricopeptide repeat-containing protein 2 (Q12118)

Analyse AlphaFold monomer V2.0 prediction for small glutamine-rich tetratricopeptide… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q12118
Type
protein
Length
346 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x422f92Ed16F3e38E0Df945A0deE92D80fCDFD0FB
Molecule
Small glutamine-rich tetratricopeptide repeat-containing protein 2
UniProt
Q12118
Pockets
1 · best druggability 0.26

Structure

1 distinct chain · 65% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASmall glutamine-rich tetratricopeptide repeat-containing protein 2protein34665% helix, 0% strandQ12118

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1500.260.7411empty

Compared structures

  • 5LYP · Crystal structure of the Tpr Domain of Sgt2. · an experimental structure of the same protein · chain A against A, TM-score 0.38
  • 5LYP · Crystal structure of the tpr domain of SGT2. · an experimental structure of the same protein · chain A against A, TM-score 0.38
  • 5LYN · Structure of the tpr domain of SGT2 in complex with yeast SSA1 peptide fragment · an experimental structure of the same protein · chain A against A, TM-score 0.38
  • 5LYN · Structure of the Tpr Domain of Sgt2 in complex with yeast Ssa1 peptide fragment · an experimental structure of the same protein · chain A against A, TM-score 0.38
  • 4ASW · Structure of the complex between the N-terminal dimerisation domain of SGT2 and the ubl… · an experimental structure of the same protein · chain A against A, TM-score 0.21
  • 4ASW · Structure of the complex between the N-terminal dimerisation domain of Sgt2 and the UBL… · an experimental structure of the same protein · chain A against A, TM-score 0.21
  • 4ASV · Solution structure of the N-terminal dimerisation domain of SGT2 · an experimental structure of the same protein · chain A against A, TM-score 0.21
  • 4ASV · Solution structure of the N-terminal dimerisation domain of Sgt2 · an experimental structure of the same protein · chain A against A, TM-score 0.21
  • 2LXB · Solution structure of the Sgt2 homodimerization domain · an experimental structure of the same protein · chain A against A, TM-score 0.18
  • 2LXB · Solution structure of the SGT2 homodimerization domain · an experimental structure of the same protein · chain A against A, TM-score 0.18
  • 3ZDM · Crystal structure of the Sgt2 N domain and the Get5 UBL domain complex · an experimental structure of the same protein · chain A against A, TM-score 0.17
  • 3ZDM · Crystal structure of the SGT2 N domain and the GET5 ubl domain complex · an experimental structure of the same protein · chain A against A, TM-score 0.17

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