UniProt Q12118
Small glutamine-rich tetratricopeptide repeat-containing protein 2 (Q12118)
Small glutamine-rich tetratricopeptide repeat-containing protein 2 (UniProt Q12118): 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, druggability and experiment against…
- UniProt
- Q12118
- Protein
- Small glutamine-rich tetratricopeptide repeat-containing protein 2
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 1 · 0 records with a druggable one
Structures
15 records of Q12118 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LXB | Solution structure of the Sgt2 homodimerization domain | solution nmr | A, B | — | — |
| 2LXB | Solution structure of the SGT2 homodimerization domain | solution nmr | A, B | — | — |
| 2LXC | Solution structure of the complex between the Sgt2 homodimerization domain and the Get5 UBL domain | solution nmr | B, C | — | — |
| 2LXC | Solution structure of the complex between the SGT2 homodimerization domain and the GET5 ubl domain | solution nmr | B, C | — | — |
| 3ZDM | Crystal structure of the Sgt2 N domain and the Get5 UBL domain complex | x-ray diffraction | A, B, D, E | — | — |
| 3ZDM | Crystal structure of the SGT2 N domain and the GET5 ubl domain complex | x-ray diffraction | A, B, D, E | — | — |
| 4ASV | Solution structure of the N-terminal dimerisation domain of Sgt2 | solution nmr | A, B | — | — |
| 4ASV | Solution structure of the N-terminal dimerisation domain of SGT2 | solution nmr | A, B | — | — |
| 4ASW | Structure of the complex between the N-terminal dimerisation domain of Sgt2 and the UBL domain of… | solution nmr | A, B | — | — |
| 4ASW | Structure of the complex between the N-terminal dimerisation domain of SGT2 and the ubl domain of… | solution nmr | A, B | — | — |
| 5LYN | Structure of the Tpr Domain of Sgt2 in complex with yeast Ssa1 peptide fragment | x-ray diffraction | A, B | ZN | — |
| 5LYN | Structure of the tpr domain of SGT2 in complex with yeast SSA1 peptide fragment | x-ray diffraction | A, B | ZN | — |
| 5LYP | Crystal structure of the Tpr Domain of Sgt2. | x-ray diffraction | A | BO4 | — |
| 5LYP | Crystal structure of the tpr domain of SGT2. | x-ray diffraction | A | BO4 | — |
| Q12118 | AlphaFold monomer V2.0 prediction for small glutamine-rich tetratricopeptide repeat-containing… | predicted | A | — | 1 (best 0.26) |
Ligands
Experiment against prediction
- 5LYN chain A against the predicted model Q12118: TM-score 0.97, RMSD 0.82 Å
- 5LYN chain A against the predicted model Q12118: TM-score 0.97, RMSD 0.82 Å
- 3ZDM chain B against the predicted model Q12118: TM-score 0.94, RMSD 0.60 Å
- 3ZDM chain B against the predicted model Q12118: TM-score 0.94, RMSD 0.60 Å
- 5LYP chain A against the predicted model Q12118: TM-score 0.94, RMSD 1.54 Å
- 5LYP chain A against the predicted model Q12118: TM-score 0.94, RMSD 1.54 Å
- 4ASW chain A against the predicted model Q12118: TM-score 0.84, RMSD 1.92 Å
- 4ASW chain A against the predicted model Q12118: TM-score 0.84, RMSD 1.92 Å
- 4ASV chain A against the predicted model Q12118: TM-score 0.84, RMSD 1.99 Å
- 4ASV chain A against the predicted model Q12118: TM-score 0.84, RMSD 1.99 Å
Elsewhere
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