Research workbench
AlphaFold monomer V2.0 prediction for helicase SEN1 (Q00416)
Analyse AlphaFold monomer V2.0 prediction for helicase SEN1 (Q00416) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q00416
- Type
- protein
- Length
- 2,231 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x55F166d9F6A3981E60dDA03De65e7EbdD73842e2
- Molecule
- Helicase SEN1
- UniProt
- Q00416
- Pockets
- 20 · best druggability 0.74
Structure
1 distinct chain · 47% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Helicase SEN1 | protein | 2231 | 47% helix, 6% strand | Q00416 |
Pockets
20 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 851 | 0.74 | 0.78 | 86 | empty |
| 2 | 795 | 0.72 | 0.78 | 75 | empty |
| 3 | 331 | 0.62 | 0.79 | 37 | empty |
| 4 | 126 | 0.45 | 0.78 | 20 | empty |
| 5 | 203 | 0.44 | 0.73 | 29 | empty |
Compared structures
- 6I59 · Long wavelength native-sad phasing of SEN1 helicase · an experimental structure of the same protein · chain A against A, TM-score 0.30
- 5MZN · Helicase Sen1 · an experimental structure of the same protein · chain A against A, TM-score 0.30
- 5MZN · Helicase SEN1 · an experimental structure of the same protein · chain A against A, TM-score 0.30
- 6GC3 · Structure of NRD1 cid - SEN1 nim complex · an experimental structure of the same protein · chain A against B, TM-score 0.00
- 6O3W · Crystal structure of yeast NRD1 cid in complex with SEN1 NIM1 · an experimental structure of the same protein · chain A against C, TM-score 0.00
- 6O3Y · Crystal structure of yeast NRD1 cid in complex with SEN1 NIM3 · an experimental structure of the same protein · chain A against D, TM-score 0.00
- 6O3X · Crystal structure of yeast NRD1 cid in complex with SEN1 NIM2 · an experimental structure of the same protein · chain A against D, TM-score 0.00
- 6O3X · Crystal structure of yeast Nrd1 CID in complex with Sen1 NIM2 · an experimental structure of the same protein · chain A against D, TM-score 0.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q00416
- Elsewhere: UniProt Q00416 · AlphaFold DB Q00416
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