UniProt Q00416
Helicase SEN1 (Q00416)
Helicase SEN1 (UniProt Q00416): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q00416
- Protein
- Helicase SEN1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
9 records of Q00416 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MZN | Helicase Sen1 | x-ray diffraction | A | ADP, MG | — |
| 5MZN | Helicase SEN1 | x-ray diffraction | A | ADP, MG | — |
| 6GC3 | Structure of NRD1 cid - SEN1 nim complex | solution nmr | B | — | — |
| 6I59 | Long wavelength native-sad phasing of SEN1 helicase | x-ray diffraction | A | ADP, MG | — |
| 6O3W | Crystal structure of yeast NRD1 cid in complex with SEN1 NIM1 | x-ray diffraction | C, D | — | — |
| 6O3X | Crystal structure of yeast Nrd1 CID in complex with Sen1 NIM2 | x-ray diffraction | D, E, F | — | — |
| 6O3X | Crystal structure of yeast NRD1 cid in complex with SEN1 NIM2 | x-ray diffraction | D, E, F | — | — |
| 6O3Y | Crystal structure of yeast NRD1 cid in complex with SEN1 NIM3 | x-ray diffraction | D, E, F | — | — |
| Q00416 | AlphaFold monomer V2.0 prediction for helicase SEN1 (Q00416) | predicted | A | — | 20 (best 0.74) |
Ligands
Experiment against prediction
- 6I59 chain A against the predicted model Q00416: TM-score 0.97, RMSD 1.90 Å
- 5MZN chain A against the predicted model Q00416: TM-score 0.97, RMSD 1.90 Å
- 5MZN chain A against the predicted model Q00416: TM-score 0.97, RMSD 1.90 Å
- 6O3X chain D against the predicted model Q00416: TM-score 0.71, RMSD 0.34 Å
- 6O3X chain D against the predicted model Q00416: TM-score 0.71, RMSD 0.34 Å
- 6O3Y chain E against the predicted model Q00416: TM-score 0.67, RMSD 0.43 Å
- 6O3Y chain D against the predicted model Q00416: TM-score 0.54, RMSD 0.61 Å
- 6O3W chain C against the predicted model Q00416: TM-score 0.48, RMSD 0.91 Å
- 6GC3 chain B against the predicted model Q00416: TM-score 0.33, RMSD 1.16 Å
Elsewhere
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