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AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase a (P37468)

Analyse AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P37468
Type
protein
Length
292 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x7782F4817b37743d738e9aF842bf74bd50f2015E
Molecule
Ribosomal RNA small subunit methyltransferase a
UniProt
P37468
Pockets
1 · best druggability 0.79

Structure

1 distinct chain · 45% helix, 18% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARibosomal RNA small subunit methyltransferase aprotein29245% helix, 18% strandP37468

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11640.790.9436empty

Compared structures

  • 6IFT · KsgA from Bacillus subtilis in complex with SAM · an experimental structure of the same protein · chain A against A, TM-score 0.99
  • 6IFT · Ksga from bacillus subtilis in complex with SAM · an experimental structure of the same protein · chain A against A, TM-score 0.99
  • 6IFS · KsgA from Bacillus subtilis 168 · an experimental structure of the same protein · chain A against B, TM-score 0.93
  • 6IFS · Ksga from bacillus subtilis 168 · an experimental structure of the same protein · chain A against B, TM-score 0.93
  • 7V2M · T.thermophilus 30S ribosome with KsgA, class K1k4 · an experimental structure of the same protein · chain A against U, TM-score 0.92
  • 7V2M · T.THERMOPHILUS 30S ribosome with ksga, class K1K4 · an experimental structure of the same protein · chain A against U, TM-score 0.92
  • 7V2P · T.THERMOPHILUS 30S ribosome with ksga, class K5 · an experimental structure of the same protein · chain A against U, TM-score 0.91
  • 7V2P · T.thermophilus 30S ribosome with KsgA, class K5 · an experimental structure of the same protein · chain A against U, TM-score 0.91
  • 6IFW · Crystal structure of chimeric construct of ksga with loop 1 from erm · an experimental structure of the same protein · chain A against A, TM-score 0.88
  • 6IFW · crystal structure of chimeric construct of KsgA with loop 1 from erm · an experimental structure of the same protein · chain A against A, TM-score 0.88

Analyse

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