UniProt P37468
Ribosomal RNA small subunit methyltransferase A (P37468)
Ribosomal RNA small subunit methyltransferase A (UniProt P37468), EC 2.1.1.182: 18 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P37468
- Protein
- Ribosomal RNA small subunit methyltransferase A
- EC
- 2.1.1.182
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 12 · 7 records with a druggable one
Structures
19 records of P37468 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6IFS | Ksga from bacillus subtilis 168 | x-ray diffraction | A, B | — | — |
| 6IFT | KsgA from Bacillus subtilis in complex with SAM | x-ray diffraction | A | — | — |
| 6IFT | Ksga from bacillus subtilis in complex with SAM | x-ray diffraction | A | — | — |
| 6IFV | C-terminal truncated ksga from bacillus subtilis 168 | x-ray diffraction | A, B | — | — |
| 6IFW | crystal structure of chimeric construct of KsgA with loop 1 from erm | x-ray diffraction | A, B | — | 2 (best 0.81) |
| 6IFW | Crystal structure of chimeric construct of ksga with loop 1 from erm | x-ray diffraction | A, B | — | — |
| 6IFX | Crystal structure of chimeric ksga with loop 12 from erm | x-ray diffraction | A, B | — | — |
| 7V2L | T.thermophilus 30S ribosome with KsgA, class K1k2 | electron microscopy | W | — | 2 (best 0.79) |
| 7V2L | T.THERMOPHILUS 30S ribosome with ksga, class K1K2 | electron microscopy | W | — | — |
| 7V2M | T.thermophilus 30S ribosome with KsgA, class K1k4 | electron microscopy | U, W | — | 3 (best 0.80) |
| 7V2M | T.THERMOPHILUS 30S ribosome with ksga, class K1K4 | electron microscopy | U, W | — | — |
| 7V2N | T.thermophilus 30S ribosome with KsgA, class K2 | electron microscopy | U | — | 1 (best 0.79) |
| 7V2N | T.THERMOPHILUS 30S ribosome with ksga, class K2 | electron microscopy | U | — | — |
| 7V2O | T.thermophilus 30S ribosome with KsgA, class K4 | electron microscopy | U | — | 2 (best 0.79) |
| 7V2O | T.THERMOPHILUS 30S ribosome with ksga, class K4 | electron microscopy | U | — | — |
| 7V2P | T.thermophilus 30S ribosome with KsgA, class K5 | electron microscopy | U | — | 1 (best 0.75) |
| 7V2P | T.THERMOPHILUS 30S ribosome with ksga, class K5 | electron microscopy | U | — | — |
| 7V2Q | T.THERMOPHILUS 30S ribosome with ksga, class K6 | electron microscopy | U, W | — | — |
| P37468 | AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase a (P37468) | predicted | A | — | 1 (best 0.79) |
Experiment against prediction
- 6IFT chain A against the predicted model P37468: TM-score 0.98, RMSD 0.93 Å
- 6IFT chain A against the predicted model P37468: TM-score 0.98, RMSD 0.93 Å
- 6IFV chain B against the predicted model P37468: TM-score 0.98, RMSD 0.91 Å
- 6IFW chain A against the predicted model P37468: TM-score 0.98, RMSD 0.97 Å
- 6IFW chain A against the predicted model P37468: TM-score 0.98, RMSD 0.97 Å
- 6IFV chain A against the predicted model P37468: TM-score 0.98, RMSD 0.96 Å
- 6IFS chain B against the predicted model P37468: TM-score 0.97, RMSD 1.02 Å
- 7V2L chain W against the predicted model P37468: TM-score 0.97, RMSD 1.05 Å
- 7V2L chain W against the predicted model P37468: TM-score 0.97, RMSD 1.05 Å
- 6IFW chain B against the predicted model P37468: TM-score 0.97, RMSD 1.04 Å
Elsewhere
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