MolNFT v1 · #152384 · protein
C-terminal truncated ksga from bacillus subtilis 168
6IFV · Ribosomal RNA small subunit methyltransferase a: “C-terminal truncated ksga from bacillus subtilis 168”. X-ray diffraction, 3 pockets (best druggability 0.66). MolNFT v1 #152384 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6IFV
- Type
- protein
- Length
- 410 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribosomal RNA small subunit methyltransferase a
- EC
- 2.1.1.182
- UniProt
- P37468
- Pockets
- 3 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosomal RNA small subunit methyltransferase a (EC 2.1.1.182) | protein | 204 | 39% helix, 25% strand | P37468 |
| B | Ribosomal RNA small subunit methyltransferase a (EC 2.1.1.182) | protein | 206 | 38% helix, 24% strand | P37468 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 279 | 0.66 | 0.82 | 42 | empty |
| 2 | 280 | 0.66 | 0.82 | 44 | empty |
| 3 | 194 | 0.53 | 0.78 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 534 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 6IFV · C-terminal truncated KsgA from Bacillus subtilis 168 · the same entry in another collection · chain A against A, TM-score 1.00
- P37468 · AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase a… · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37468
- Elsewhere: RCSB PDB 6IFV · PDBe 6IFV · UniProt P37468
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