AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor ATP- dependent RNA helicase PRP22 (P24384)

Structure

1 distinct chain · 43% helix, 15% strand (DSSP).

Pockets

17 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Compared structures

• 9DTR · Structure of the yeast post-catalytic P complex spliceosome at 2.3 Angstrom resolution · an experimental structure of the same protein · chain A against V, TM-score 0.60
• 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against V, TM-score 0.53
• 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against V, TM-score 0.53
• 5YLZ · Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against W, TM-score 0.53
• 5YLZ · Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against W, TM-score 0.53
• 5MQ0 · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against V, TM-score 0.53
• 5MQ0 · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against V, TM-score 0.53
• 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against P, TM-score 0.52
• 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against P, TM-score 0.52

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P24384
• Elsewhere: UniProt P24384 · AlphaFold DB P24384