AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor PRP21 (P32524)

Structure

1 distinct chain · 50% helix, 0% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 5NRL · Structure of a pre-catalytic spliceosome · an experimental structure of the same protein · chain A against V, TM-score 0.45
• 5ZWM · Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom… · an experimental structure of the same protein · chain A against w, TM-score 0.45
• 4DGW · Crystal Structure of the SF3a splicing factor complex of U2 snRNP · an experimental structure of the same protein · chain A against B, TM-score 0.45
• 4DGW · Crystal structure of the SF3A splicing factor complex of U2 snrnp · an experimental structure of the same protein · chain A against B, TM-score 0.45
• 6G90 · Prespliceosome structure provides insight into spliceosome assembly and regulation (MAP… · an experimental structure of the same protein · chain A against V, TM-score 0.45
• 6G90 · Prespliceosome structure provides insight into spliceosome assembly and regulation (map… · an experimental structure of the same protein · chain A against V, TM-score 0.45
• 5ZWO · Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström · an experimental structure of the same protein · chain A against w, TM-score 0.45
• 5ZWO · Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom · an experimental structure of the same protein · chain A against w, TM-score 0.45
• 7DCO · Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of… · an experimental structure of the same protein · chain A against w, TM-score 0.45
• 7OQE · Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) · an experimental structure of the same protein · chain A against V, TM-score 0.32
• 7OQE · Saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) · an experimental structure of the same protein · chain A against V, TM-score 0.32
• 7OQB · The U2 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) · an experimental structure of the same protein · chain A against V, TM-score 0.32

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P32524
• Elsewhere: UniProt P32524 · AlphaFold DB P32524