UniProt P32524
Pre-mRNA-splicing factor PRP21 (P32524)
Pre-mRNA-splicing factor PRP21 (UniProt P32524): 11 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32524
- Protein
- Pre-mRNA-splicing factor PRP21
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
12 records of P32524 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DGW | Crystal Structure of the SF3a splicing factor complex of U2 snRNP | x-ray diffraction | B | — | — |
| 4DGW | Crystal structure of the SF3A splicing factor complex of U2 snrnp | x-ray diffraction | B | — | — |
| 5NRL | Structure of a pre-catalytic spliceosome | electron microscopy | V | — | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | electron microscopy | w | — | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström | electron microscopy | w | — | — |
| 6G90 | Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2) | electron microscopy | V | — | — |
| 6G90 | Prespliceosome structure provides insight into spliceosome assembly and regulation (MAP A2) | electron microscopy | V | — | — |
| 7DCO | Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5… | electron microscopy | w | — | — |
| 7OQB | The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | electron microscopy | V | — | — |
| 7OQB | The U2 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | V | — | — |
| 7OQE | Saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | V | — | — |
| P32524 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor PRP21 (P32524) | predicted | A | — | 1 (best 0.30) |
Experiment against prediction
- 5NRL chain V against the predicted model P32524: TM-score 0.99, RMSD 0.52 Å
- 4DGW chain B against the predicted model P32524: TM-score 0.99, RMSD 0.52 Å
- 4DGW chain B against the predicted model P32524: TM-score 0.99, RMSD 0.52 Å
- 6G90 chain V against the predicted model P32524: TM-score 0.99, RMSD 0.52 Å
- 6G90 chain V against the predicted model P32524: TM-score 0.99, RMSD 0.52 Å
- 5ZWO chain w against the predicted model P32524: TM-score 0.99, RMSD 0.52 Å
- 5ZWO chain w against the predicted model P32524: TM-score 0.99, RMSD 0.52 Å
- 7DCO chain w against the predicted model P32524: TM-score 0.98, RMSD 0.64 Å
- 7OQE chain V against the predicted model P32524: TM-score 0.84, RMSD 1.55 Å
- 7OQB chain V against the predicted model P32524: TM-score 0.84, RMSD 1.55 Å
Elsewhere
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